Cobamamide

BLOOD AND BLOOD FORMING ORGANS

Key facts

Cobamamide is a drug catalogued in DrugCentral. Recorded indications include Prevention of Vitamin B12 Deficiency.

• Indications: Prevention of Vitamin B12 Deficiency.
• ATC code: B03BA04 (Vitamin B12 (cyanocobalamin and analogues)).
• Molecular formula: C72H100CoN18O17P; molecular weight 1579.61 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Prevention of Vitamin B12 Deficiency

Contraindications (4)

• Atrophic gastritis
• Gastrectomy
• Hypokalemia
• Leber's optic atrophy

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
B03BA04	BLOOD AND BLOOD FORMING ORGANS › ANTIANEMIC PREPARATIONS › VITAMIN B12 AND FOLIC ACID › Vitamin B12 (cyanocobalamin and analogues)

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Ejection fraction abnormal	113.7
Sensitisation	110.2
Ultrasound antenatal screen	105.7
Polycystic ovaries	103.6
Trisomy 18	99.4
Hydrops foetalis	95.3
Needle fatigue	85.5
Cleft lip and palate	82.9
Gait spastic	81.5
Relapsing-remitting multiple sclerosis	76.1
Carpal tunnel syndrome	72.4
Ejection fraction	71.5

Chemical structure

• Molecular formula: C₇₂H₁₀₀CoN₁₈O₁₇P
• Molecular weight: 1579.61 g/mol
• CAS number: 13870-90-1
• InChIKey: —
• PubChem CID: 131635025

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Cobamamide used for?

DrugCentral lists the following indications for Cobamamide: Prevention of Vitamin B12 Deficiency.

What is the chemical formula of Cobamamide?

Cobamamide has the molecular formula C72H100CoN18O17P and a molecular weight of 1579.61 g/mol.

Sources

• DrugCentral drug card 4404 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL3833359 — compound record and bioactivity
• PubChem CID 131635025 — chemical identifiers
• DrugBank DB11191 — drug record
• FDA UNII F0R1QK73KB — substance identity
• DailyMed: FDA labels for Cobamamide — current prescribing information (label search)
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

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