Mecobalamin
BLOOD AND BLOOD FORMING ORGANS
Also known as: methycobal, methyl cobalamine, Methyl vitamin B12, methylcobalamin, methylcobaz
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Mecobalamin is a drug catalogued in DrugCentral. Recorded indications include Prevention of Vitamin B12 Deficiency.
- Indications: Prevention of Vitamin B12 Deficiency.
- ATC code: B03BA05 (Vitamin B12 (cyanocobalamin and analogues)).
- Molecular formula: C63H91CoN13O14P; molecular weight 1344.40 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Prevention of Vitamin B12 Deficiency
Contraindications (4)
- Atrophic gastritis
- Gastrectomy
- Hypokalemia
- Leber's optic atrophy
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| — | FDA | — | — |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
B03BA05 | BLOOD AND BLOOD FORMING ORGANS › ANTIANEMIC PREPARATIONS › VITAMIN B12 AND FOLIC ACID › Vitamin B12 (cyanocobalamin and analogues) |
Reported adverse-event signals
Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.
| MedDRA term | LLR |
|---|---|
| Platelet count decreased | 210.1 |
| Off label use | 191.5 |
| Product use in unapproved indication | 191.2 |
| Pemphigus | 184.9 |
| Treatment failure | 182.3 |
| Hand deformity | 179.0 |
| Drug ineffective | 173.9 |
| White blood cell count decreased | 167.5 |
| Systemic lupus erythematosus | 162.4 |
| Diarrhoea | 152.6 |
| Contraindicated product administered | 141.5 |
| Plasma cell myeloma | 137.6 |
Chemical structure
| Molecular formula | C63H91CoN13O14P |
|---|---|
| Molecular weight | 1344.40 g/mol |
| CAS number | 13422-55-4 |
| InChIKey | — |
| PubChem CID | 73415798 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Mecobalamin used for?
DrugCentral lists the following indications for Mecobalamin: Prevention of Vitamin B12 Deficiency.
What is the chemical formula of Mecobalamin?
Mecobalamin has the molecular formula C63H91CoN13O14P and a molecular weight of 1344.40 g/mol.
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Sources
- DrugCentral drug card 4600 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL2359370 — compound record and bioactivity
- PubChem CID 73415798 — chemical identifiers
- DrugBank DB03614 — drug record
- FDA UNII BR1SN1JS2W — substance identity
- DailyMed: FDA labels for Mecobalamin — current prescribing information (label search)
- FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral
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