Diosmin

CARDIOVASCULAR SYSTEM

Key facts

Diosmin is a drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including IKBKB and KDM1A.

• Molecular targets: IKBKB and KDM1A (2 listed in DrugCentral).
• ATC code: C05CA03 (Bioflavonoids).
• Molecular formula: C28H32O15; molecular weight 608.55 g/mol.

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Inhibitor of nuclear factor kappa-B kinase subunit beta	IKBKB	unknown	IC50 5.41
Lysine-specific histone demethylase 1A	KDM1A	unknown	IC50 4.99

ATC classification

ATC code	Therapeutic hierarchy
C05CA03	CARDIOVASCULAR SYSTEM › VASOPROTECTIVES › CAPILLARY STABILIZING AGENTS › Bioflavonoids
C05CA53	CARDIOVASCULAR SYSTEM › VASOPROTECTIVES › CAPILLARY STABILIZING AGENTS › Bioflavonoids

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Blood lactic acid	89.5
Tubulointerstitial nephritis and uveitis syndrome	68.3
Erysipelas	60.7
Myoglobin blood increased	40.4
Hypercapnia	40.0
Lentigo maligna	36.0
Ventricular tachycardia	34.8
Cardiac arrest	25.3
Delirium	24.8
Drug interaction	23.4
Lower respiratory tract congestion	22.4
Splenic vein thrombosis	22.4

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Diosmin is on its molecule page.

• Molecular formula: C₂₈H₃₂O₁₅
• Molecular weight: 608.55 g/mol
• CAS number: —
• InChIKey: GZSOSUNBTXMUFQ-YFAPSIMESA-N
• PubChem CID: 5281613

COC1=C(O)C=C(C=C1)C1=CC(=O)C2=C(O)C=C(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)C=C2O1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Diosmin work?

Its molecular targets in DrugCentral include IKBKB and KDM1A.

What is the chemical formula of Diosmin?

Diosmin has the molecular formula C28H32O15 and a molecular weight of 608.55 g/mol.

Sources

• DrugCentral drug card 3157 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL231884 — compound record and bioactivity
• PubChem CID 5281613 — chemical identifiers
• DrugBank DB08995 — drug record
• FDA UNII 7QM776WJ5N — substance identity
• UniProt O14920 (IKBKB) — target protein
• UniProt O60341 (KDM1A) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.