Rutoside

CARDIOVASCULAR SYSTEM

Key facts

Rutoside is a drug catalogued in DrugCentral. DrugCentral lists 18 molecular targets, including BACE1, ACHE and CHRM5. Recorded indications include Ascorbic acid deficiency.

• Molecular targets: BACE1, ACHE, CHRM5 and HMGB1 (18 listed in DrugCentral).
• Indications: Ascorbic acid deficiency.
• ATC code: C05CA01 (Bioflavonoids).
• Molecular formula: C27H30O16; molecular weight 610.52 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Ascorbic acid deficiency

Off-label uses (1)

• Methemoglobinemia

Contraindications (4)

• Anemia due to enzyme deficiency
• Hb SS disease
• Hemochromatosis
• Primary hyperoxaluria

Mechanism & targets

Molecular targets (18)

Target	Gene	Action	Activity
Beta-secretase 1	BACE1	unknown	IC50 8.42
Acetylcholinesterase	ACHE	unknown	IC50 7.92
Muscarinic acetylcholine receptor M5	CHRM5	unknown	Ki 7.45
High mobility group protein B1	HMGB1	unknown	Kd 6.58
Neuromedin-U receptor 2	NMUR2	unknown	EC50 5.92
Lysine-specific histone demethylase 1A	KDM1A	unknown	IC50 5.67
Amine oxidase [flavin-containing] A	MAOA	unknown	IC50 5.41
Alpha-2A adrenergic receptor	ADRA2A	unknown	Ki 5.03
Alpha-2C adrenergic receptor	ADRA2C	unknown	Ki 5.02
Aldose reductase	Akr1b1	unknown	IC50 4.89
Bifunctional epoxide hydrolase 2	EPHX2	unknown	IC50 4.61
Sialidase	nanH	unknown	IC50 4.51
Neuraminidase	—	unknown	Ki 4.47
Serum albumin	ALB	unknown	IC50 4.38
Xanthine dehydrogenase/oxidase	XDH	unknown	IC50 4.28
Cystic fibrosis transmembrane conductance regulator	CFTR	unknown	Kd 4.18
Polyphenol oxidase 2	PPO2	unknown	IC50 4.16
Neuraminidase	—	unknown	IC50 4.02

ATC classification

ATC code	Therapeutic hierarchy
C05CA01	CARDIOVASCULAR SYSTEM › VASOPROTECTIVES › CAPILLARY STABILIZING AGENTS › Bioflavonoids
C05CA51	CARDIOVASCULAR SYSTEM › VASOPROTECTIVES › CAPILLARY STABILIZING AGENTS › Bioflavonoids

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Rutoside is on its molecule page.

• Molecular formula: C₂₇H₃₀O₁₆
• Molecular weight: 610.52 g/mol
• CAS number: 153-18-4
• InChIKey: IKGXIBQEEMLURG-NVPNHPEKSA-N
• PubChem CID: 5280805

C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC3=C(OC4=CC(O)=CC(O)=C4C3=O)C3=CC(O)=C(O)C=C3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Rutoside used for?

DrugCentral lists the following indications for Rutoside: Ascorbic acid deficiency.

How does Rutoside work?

Its molecular targets in DrugCentral include BACE1, ACHE, CHRM5 and HMGB1.

What is the chemical formula of Rutoside?

Rutoside has the molecular formula C27H30O16 and a molecular weight of 610.52 g/mol.

Sources

• DrugCentral drug card 3535 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL226335 — compound record and bioactivity
• PubChem CID 5280805 — chemical identifiers
• DrugBank DB01698 — drug record
• FDA UNII 5G06TVY3R7 — substance identity
• UniProt P56817 (BACE1) — target protein
• UniProt P22303 (ACHE) — target protein
• UniProt P08912 (CHRM5) — target protein
• UniProt P09429 (HMGB1) — target protein
• UniProt Q9GZQ4 (NMUR2) — target protein
• UniProt O60341 (KDM1A) — target protein

How this page is built: methodology · editorial policy & corrections.