Doxecitine

ALIMENTARY TRACT AND METABOLISM

Key facts

Doxecitine is an onp drug catalogued in DrugCentral. It was first approved by the FDA in 2025. DrugCentral lists 1 molecular target, including pol. Recorded indications include Thymidine kinase 2 deficiency.

• Approval status: onp (first approved 2025 by the FDA).
• Molecular targets: pol (1 listed in DrugCentral).
• Indications: Thymidine kinase 2 deficiency.
• ATC code: A16AX29 (Various alimentary tract and metabolism products).
• Molecular formula: C9H13N3O4; molecular weight 227.22 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Thymidine kinase 2 deficiency

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Reverse transcriptase/RNaseH	pol	unknown	Kd 5.96

Regulatory approvals (2)

Date	Agency	Marketed as	Applicant	Orphan
2026-03-26	EMA	—	UCB Pharma	Yes
2025-11-11	FDA	—	UCB Inc	Yes

ATC classification

ATC code	Therapeutic hierarchy
A16AX29	ALIMENTARY TRACT AND METABOLISM › OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS › OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS › Various alimentary tract and metabolism products

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Doxecitine is on its molecule page.

• Molecular formula: C₉H₁₃N₃O₄
• Molecular weight: 227.22 g/mol
• CAS number: —
• InChIKey: CKTSBUTUHBMZGZ-SHYZEUOFSA-N
• PubChem CID: 13711

C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Doxecitine used for?

DrugCentral lists the following indications for Doxecitine: Thymidine kinase 2 deficiency.

How does Doxecitine work?

Its molecular targets in DrugCentral include pol.

When was Doxecitine first approved?

Doxecitine was first approved by the FDA in 2025.

What is the chemical formula of Doxecitine?

Doxecitine has the molecular formula C9H13N3O4 and a molecular weight of 227.22 g/mol.

Sources

• DrugCentral drug card 5786 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL66115 — compound record and bioactivity
• PubChem CID 13711 — chemical identifiers
• DrugBank DB02594 — drug record
• FDA UNII 0W860991D6 — substance identity
• DailyMed: FDA labels for Doxecitine — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.