Doxribtimine

ALIMENTARY TRACT AND METABOLISM

Key facts

Doxribtimine is an onp drug catalogued in DrugCentral. It was first approved by the FDA in 2025. DrugCentral lists 2 molecular targets, including UL23 and tmk. Recorded indications include Thymidine kinase 2 deficiency.

• Approval status: onp (first approved 2025 by the FDA).
• Molecular targets: UL23 and tmk (2 listed in DrugCentral).
• Indications: Thymidine kinase 2 deficiency.
• ATC code: A16AX29 (Various alimentary tract and metabolism products).
• Molecular formula: C10H14N2O5; molecular weight 242.23 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Thymidine kinase 2 deficiency

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Thymidine kinase	UL23	unknown	IC50 5.39
Thymidylate kinase	tmk	unknown	Ki 4.57

Regulatory approvals (2)

Date	Agency	Marketed as	Applicant	Orphan
2026-03-26	EMA	—	UCB Pharma	Yes
2025-11-03	FDA	—	UCB Inc	Yes

ATC classification

ATC code	Therapeutic hierarchy
A16AX29	ALIMENTARY TRACT AND METABOLISM › OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS › OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS › Various alimentary tract and metabolism products

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Doxribtimine is on its molecule page.

• Molecular formula: C₁₀H₁₄N₂O₅
• Molecular weight: 242.23 g/mol
• CAS number: —
• InChIKey: IQFYYKKMVGJFEH-XLPZGREQSA-N
• PubChem CID: 5789

CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Doxribtimine used for?

DrugCentral lists the following indications for Doxribtimine: Thymidine kinase 2 deficiency.

How does Doxribtimine work?

Its molecular targets in DrugCentral include UL23 and tmk.

When was Doxribtimine first approved?

Doxribtimine was first approved by the FDA in 2025.

What is the chemical formula of Doxribtimine?

Doxribtimine has the molecular formula C10H14N2O5 and a molecular weight of 242.23 g/mol.

Sources

• DrugCentral drug card 5787 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL52609 — compound record and bioactivity
• PubChem CID 5789 — chemical identifiers
• DrugBank DB04485 — drug record
• FDA UNII VC2W18DGKR — substance identity
• DailyMed: FDA labels for Doxribtimine — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.