Iodixanol

Radiographic Contrast Agent — VARIOUS

Key facts

Iodixanol is a drug in the Radiographic Contrast Agent class catalogued in DrugCentral. It was first approved by the FDA in 1996. Its mechanism of action is classified as X-Ray Contrast Activity.

• Drug class: Radiographic Contrast Agent.
• Mechanism of action: X-Ray Contrast Activity.
• ATC code: V08AB09 (Watersoluble, nephrotropic, low osmolar X-ray contrast media).
• Molecular formula: C35H44I6N6O15; molecular weight 1550.19 g/mol.

Mechanism & targets

• Mechanism of action (MoA): X-Ray Contrast Activity
• Established pharmacologic class: Radiographic Contrast Agent

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1996-03-22	FDA	—	GE HEALTHCARE

ATC classification

ATC code	Therapeutic hierarchy
V08AB09	VARIOUS › CONTRAST MEDIA › X-RAY CONTRAST MEDIA, IODINATED › Watersoluble, nephrotropic, low osmolar X-ray contrast media

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Pruritus	596.4
Contrast media allergy	523.2
Erythema	392.0
Contrast media reaction	387.8
Acute generalised exanthematous pustulosis	289.9
Urticaria	287.6
Contrast encephalopathy	227.9
Rash	224.9
Anaphylactic reaction	219.1
Rash maculo-papular	204.8
Acute kidney injury	177.0
Swelling face	153.5

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Iodixanol is on its molecule page.

• Molecular formula: C₃₅H₄₄I₆N₆O₁₅
• Molecular weight: 1550.19 g/mol
• CAS number: —
• InChIKey: NBQNWMBBSKPBAY-UHFFFAOYSA-N
• PubChem CID: 3724

CC(=O)N(CC(O)CN(C(C)=O)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Iodixanol work?

Iodixanol is classified as X-Ray Contrast Activity.

When was Iodixanol first approved?

Iodixanol was first approved by the FDA in 1996.

What drug class does Iodixanol belong to?

Iodixanol is in the Radiographic Contrast Agent class.

What is the chemical formula of Iodixanol?

Iodixanol has the molecular formula C35H44I6N6O15 and a molecular weight of 1550.19 g/mol.

Sources

• DrugCentral drug card 3302 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200507 — compound record and bioactivity
• PubChem CID 3724 — chemical identifiers
• DrugBank DB01249 — drug record
• FDA UNII HW8W27HTXX — substance identity
• DailyMed: FDA labels for Iodixanol — current prescribing information (label search)
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.