Ioversol

Radiographic Contrast Agent — VARIOUS

Key facts

Ioversol is an ofp drug in the Radiographic Contrast Agent class catalogued in DrugCentral. It was first approved by the FDA in 1988. Its mechanism of action is classified as X-Ray Contrast Activity.

• Approval status: ofp (first approved 1988 by the FDA).
• Drug class: Radiographic Contrast Agent.
• Mechanism of action: X-Ray Contrast Activity.
• ATC code: V08AB07 (Watersoluble, nephrotropic, low osmolar X-ray contrast media).
• Molecular formula: C18H24I3N3O9; molecular weight 807.11 g/mol.

Mechanism & targets

• Mechanism of action (MoA): X-Ray Contrast Activity
• Established pharmacologic class: Radiographic Contrast Agent

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1988-12-30	FDA	—	LIEBEL-FLARSHEIM

ATC classification

ATC code	Therapeutic hierarchy
V08AB07	VARIOUS › CONTRAST MEDIA › X-RAY CONTRAST MEDIA, IODINATED › Watersoluble, nephrotropic, low osmolar X-ray contrast media

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Urticaria	1063.2
Sneezing	664.6
Nephropathy toxic	595.5
Pruritus	572.7
Throat irritation	564.4
Anaphylactic shock	433.1
Throat tightness	379.1
Dyspnoea	339.3
Contrast media reaction	324.6
Air embolism	284.7
Erythema	278.5
Chest discomfort	232.5

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Ioversol is on its molecule page.

• Molecular formula: C₁₈H₂₄I₃N₃O₉
• Molecular weight: 807.11 g/mol
• CAS number: —
• InChIKey: AMDBBAQNWSUWGN-UHFFFAOYSA-N
• PubChem CID: 3741

OCCN(C(=O)CO)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Ioversol work?

Ioversol is classified as X-Ray Contrast Activity.

When was Ioversol first approved?

Ioversol was first approved by the FDA in 1988.

What drug class does Ioversol belong to?

Ioversol is in the Radiographic Contrast Agent class.

What is the chemical formula of Ioversol?

Ioversol has the molecular formula C18H24I3N3O9 and a molecular weight of 807.11 g/mol.

Sources

• DrugCentral drug card 1471 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200614 — compound record and bioactivity
• PubChem CID 3741 — chemical identifiers
• DrugBank DB09134 — drug record
• FDA UNII N3RIB7X24K — substance identity
• DailyMed: FDA labels for Ioversol — current prescribing information (label search)
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.