Iohexol

Radiographic Contrast Agent — VARIOUS

Key facts

Iohexol is an ofp drug in the Radiographic Contrast Agent class catalogued in DrugCentral. It was first approved by the FDA in 1985. Its mechanism of action is classified as X-Ray Contrast Activity.

• Approval status: ofp (first approved 1985 by the FDA).
• Drug class: Radiographic Contrast Agent.
• Mechanism of action: X-Ray Contrast Activity.
• ATC code: V08AB02 (Watersoluble, nephrotropic, low osmolar X-ray contrast media).
• Molecular formula: C19H26I3N3O9; molecular weight 821.14 g/mol.

Mechanism & targets

• Mechanism of action (MoA): X-Ray Contrast Activity
• Established pharmacologic class: Radiographic Contrast Agent

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1985-12-26	FDA	—	GE HEALTHCARE

ATC classification

ATC code	Therapeutic hierarchy
V08AB02	VARIOUS › CONTRAST MEDIA › X-RAY CONTRAST MEDIA, IODINATED › Watersoluble, nephrotropic, low osmolar X-ray contrast media

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Sneezing	2032.2
Urticaria	1726.3
Contrast media reaction	1254.3
Contrast media allergy	1044.2
Pruritus	1007.1
Erythema	863.8
Extravasation	515.8
Throat irritation	504.4
Throat tightness	490.9
Anaphylactic reaction	416.5
Chills	399.5
Dyspnoea	368.9

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Iohexol is on its molecule page.

• Molecular formula: C₁₉H₂₆I₃N₃O₉
• Molecular weight: 821.14 g/mol
• CAS number: —
• InChIKey: NTHXOOBQLCIOLC-UHFFFAOYSA-N
• PubChem CID: 3730

CC(=O)N(CC(O)CO)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Iohexol work?

Iohexol is classified as X-Ray Contrast Activity.

When was Iohexol first approved?

Iohexol was first approved by the FDA in 1985.

What drug class does Iohexol belong to?

Iohexol is in the Radiographic Contrast Agent class.

What is the chemical formula of Iohexol?

Iohexol has the molecular formula C19H26I3N3O9 and a molecular weight of 821.14 g/mol.

Sources

• DrugCentral drug card 1461 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200455 — compound record and bioactivity
• PubChem CID 3730 — chemical identifiers
• DrugBank DB01362 — drug record
• FDA UNII 4419T9MX03 — substance identity
• DailyMed: FDA labels for Iohexol — current prescribing information (label search)
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.