Levamlodipine
CARDIOVASCULAR SYSTEM
Also known as: (S)-amlodipine, l-Amlodipine, levamlodipine besylate, levamlodipine malate, levoamlodipine
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Levamlodipine is an ofp drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including CACNA1D|CACNA1C.
- Approval status: ofp.
- Molecular targets: CACNA1D|CACNA1C (1 listed in DrugCentral).
- ATC code: C08CA17 (Dihydropyridine derivatives).
- Molecular formula: C20H25ClN2O5; molecular weight 408.88 g/mol.
Mechanism & targets
Molecular targets (1)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Voltage-gated L-type calcium channel | CACNA1D|CACNA1C | blocker | — |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
C08CA17 | CARDIOVASCULAR SYSTEM › CALCIUM CHANNEL BLOCKERS › SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS › Dihydropyridine derivatives |
Reported adverse-event signals
Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.
| MedDRA term | LLR |
|---|---|
| Blood urea increased | 45.1 |
| Neutrophil count increased | 43.7 |
| Lymphocyte count decreased | 40.8 |
| Incision site pain | 34.0 |
Chemical structure
| Molecular formula | C20H25ClN2O5 |
|---|---|
| Molecular weight | 408.88 g/mol |
| CAS number | 103129-82-4 |
| InChIKey | HTIQEAQVCYTUBX-KRWDZBQOSA-N |
| PubChem CID | 9822750 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
How does Levamlodipine work?
Its molecular targets in DrugCentral include CACNA1D|CACNA1C (blocker).
What is the chemical formula of Levamlodipine?
Levamlodipine has the molecular formula C20H25ClN2O5 and a molecular weight of 408.88 g/mol.
Browse: all drugs starting with L · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 4099 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL2107350 — compound record and bioactivity
- PubChem CID 9822750 — chemical identifiers
- DrugBank DB09237 — drug record
- FDA UNII 0P6NLP6806 — substance identity
- FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral
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