Linzagolix

SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS

Key facts

Linzagolix is a drug catalogued in DrugCentral. It was first approved by the EMA in 2022. DrugCentral lists 1 molecular target, including GNRHR. Recorded indications include Uterine fibroids.

• Molecular targets: GNRHR (1 listed in DrugCentral).
• Indications: Uterine fibroids.
• ATC code: H01CC04 (Anti-gonadotropin-releasing hormones).
• Molecular formula: C22H15F3N2O7S; molecular weight 508.43 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Uterine fibroids

Contraindications (4)

• Breastfeeding (mother)
• Genital bleeding
• Osteoporosis
• Pregnancy, function

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Gonadotropin-releasing hormone receptor	GNRHR	antagonist	Ki 7.56

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
2022-06-14	EMA	—	OBSEVA IRELAND LTD

ATC classification

ATC code	Therapeutic hierarchy
H01CC04	SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS › PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES › HYPOTHALAMIC HORMONES › Anti-gonadotropin-releasing hormones

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Linzagolix is on its molecule page.

• Molecular formula: C₂₂H₁₅F₃N₂O₇S
• Molecular weight: 508.43 g/mol
• CAS number: —
• InChIKey: BMAAMIIYNNPHAB-UHFFFAOYSA-N
• PubChem CID: 16656889

COC1=CC=C(F)C(F)=C1COC1=CC(N2C(=O)NC3=CSC(C(O)=O)=C3C2=O)=C(F)C=C1OC

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Linzagolix used for?

DrugCentral lists the following indications for Linzagolix: Uterine fibroids.

How does Linzagolix work?

Its molecular targets in DrugCentral include GNRHR (antagonist).

When was Linzagolix first approved?

Linzagolix was first approved by the EMA in 2022.

What is the chemical formula of Linzagolix?

Linzagolix has the molecular formula C22H15F3N2O7S and a molecular weight of 508.43 g/mol.

Sources

• DrugCentral drug card 5701 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL3668014 — compound record and bioactivity
• PubChem CID 16656889 — chemical identifiers
• DrugBank DB17083 — drug record
• FDA UNII 7CDW97HUEX — substance identity
• UniProt P30968 (GNRHR) — target protein

How this page is built: methodology · editorial policy & corrections.