Methionine

VARIOUS

Key facts

Methionine is a drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including luxS.

• Molecular targets: luxS (1 listed in DrugCentral).
• ATC code: V03AB26 (Antidotes).
• Molecular formula: C5H11NO2S; molecular weight 149.21 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Contraindications (14)

• Classical phenylketonuria
• Diabetes mellitus
• End stage renal disease
• Heart disease
• Humoral hypercalcemia of malignancy
• Hypercalcemia
• Hypercalciuria
• Hyperlipidemia
• Hypertensive disorder
• Kidney disease
• Kidney stone
• Poisoning by digitalis glycoside
• Sarcoidosis
• Ventricular fibrillation

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
S-ribosylhomocysteine lyase	luxS	unknown	Ki 4.21

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
V03AB26	VARIOUS › ALL OTHER THERAPEUTIC PRODUCTS › ALL OTHER THERAPEUTIC PRODUCTS › Antidotes
V09IX13	VARIOUS › DIAGNOSTIC RADIOPHARMACEUTICALS › TUMOUR DETECTION › Other diagnostic radiopharmaceuticals for tumour detection

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Foetal growth restriction	92.0
Ureteric dilatation	61.0
Device related sepsis	44.4
Infantile apnoea	38.8
Electrolyte imbalance	38.8
Pyelocaliectasis	38.3
Paraplegia	36.5
Gaze palsy	36.4
Selective eating disorder	35.6
Quadriplegia	34.9
Paresis	33.7
Faecaloma	33.1

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Methionine is on its molecule page.

• Molecular formula: C₅H₁₁NO₂S
• Molecular weight: 149.21 g/mol
• CAS number: 63-68-3
• InChIKey: FFEARJCKVFRZRR-BYPYZUCNSA-N
• PubChem CID: 6137

CSCC[C@H](N)C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Methionine work?

Its molecular targets in DrugCentral include luxS.

What is the chemical formula of Methionine?

Methionine has the molecular formula C5H11NO2S and a molecular weight of 149.21 g/mol.

Sources

• DrugCentral drug card 3347 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL274119 — compound record and bioactivity
• PubChem CID 6137 — chemical identifiers
• DrugBank DB00134 — drug record
• FDA UNII AE28F7PNPL — substance identity
• DailyMed: FDA labels for Methionine — current prescribing information (label search)
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.