Ethanol
DERMATOLOGICALS
Also known as: alcohol, ethyl alcohol, grain alcohol
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Ethanol is a drug catalogued in DrugCentral. It was first approved by the FDA in 1946. DrugCentral lists 4 molecular targets, including GRIN3A, GLRA1 and GLRA2. Recorded indications include Antiseptic preparation.
- Molecular targets: GRIN3A, GLRA1, GLRA2 and GABRD|GABRB2|GABRA4 (4 listed in DrugCentral).
- Indications: Antiseptic preparation.
- ATC code: D08AX08 (Other antiseptics and disinfectants).
- Molecular formula: C2H6O; molecular weight 46.07 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Antiseptic preparation
Mechanism & targets
Molecular targets (4)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 3A | GRIN3A | unknown | — |
| Glycine receptor subunit alpha-1 | GLRA1 | unknown | — |
| Glycine receptor subunit alpha-2 | GLRA2 | unknown | — |
| GABA A receptor alpha-4/beta-2/delta | GABRD|GABRB2|GABRA4 | unknown | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 1946-01-17 | FDA | — | B BRAUN |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
D08AX08 | DERMATOLOGICALS › ANTISEPTICS AND DISINFECTANTS › ANTISEPTICS AND DISINFECTANTS › Other antiseptics and disinfectants |
V03AB16 | VARIOUS › ALL OTHER THERAPEUTIC PRODUCTS › ALL OTHER THERAPEUTIC PRODUCTS › Antidotes |
V03AZ01 | VARIOUS › ALL OTHER THERAPEUTIC PRODUCTS › ALL OTHER THERAPEUTIC PRODUCTS › Nerve depressants |
Reported adverse-event signals
Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.
| MedDRA term | LLR |
|---|---|
| Completed suicide | 15420.0 |
| Drug abuse | 12409.8 |
| Toxicity to various agents | 8947.8 |
| Cardio-respiratory arrest | 2708.5 |
| Intentional overdose | 1964.6 |
| Respiratory arrest | 1692.3 |
| Poisoning | 1682.4 |
| Intentional product misuse | 1242.8 |
| Overdose | 1233.9 |
| Alcohol interaction | 1185.8 |
| Suspected suicide | 1107.8 |
| Suicide attempt | 1032.5 |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Ethanol is on its molecule page.
| Molecular formula | C2H6O |
|---|---|
| Molecular weight | 46.07 g/mol |
| CAS number | — |
| InChIKey | LFQSCWFLJHTTHZ-UHFFFAOYSA-N |
| PubChem CID | 702 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Ethanol used for?
DrugCentral lists the following indications for Ethanol: Antiseptic preparation.
How does Ethanol work?
Its molecular targets in DrugCentral include GRIN3A, GLRA1, GLRA2 and GABRD|GABRB2|GABRA4.
When was Ethanol first approved?
Ethanol was first approved by the FDA in 1946.
What is the chemical formula of Ethanol?
Ethanol has the molecular formula C2H6O and a molecular weight of 46.07 g/mol.
Browse: all drugs starting with E · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 1076 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL545 — compound record and bioactivity
- PubChem CID 702 — chemical identifiers
- DrugBank DB00898 — drug record
- FDA UNII 3K9958V90M — substance identity
- DailyMed: FDA labels for Ethanol — current prescribing information (label search)
- UniProt Q8TCU5 (GRIN3A) — target protein
- UniProt P23415 (GLRA1) — target protein
- UniProt P23416 (GLRA2) — target protein
- FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral
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