Palmidrol
Drug profile
Also known as: palmitic acid monoethanolamide, palmitic monoethanolamide, palmitoylethanolamide
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Palmidrol is a drug catalogued in DrugCentral. DrugCentral lists 4 molecular targets, including GPR55, CNR1 and CNR2.
- Molecular targets: GPR55, CNR1, CNR2 and Faah (4 listed in DrugCentral).
- Molecular formula: C18H37NO2; molecular weight 299.50 g/mol.
Mechanism & targets
Molecular targets (4)
| Target | Gene | Action | Activity |
|---|---|---|---|
| G-protein coupled receptor 55 | GPR55 | agonist | EC50 8.40 |
| Cannabinoid receptor 1 | CNR1 | unknown | Ki 5.30 |
| Cannabinoid receptor 2 | CNR2 | unknown | Ki 5.30 |
| Fatty-acid amide hydrolase 1 | Faah | unknown | IC50 5.30 |
Reported adverse-event signals
Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.
| MedDRA term | LLR |
|---|---|
| Body tinea | 340.2 |
| Infection susceptibility increased | 302.2 |
| Poor quality sleep | 301.8 |
| Inhibitory drug interaction | 288.4 |
| Glucose tolerance impaired | 259.8 |
| Impaired quality of life | 249.4 |
| Impaired work ability | 246.7 |
| Bone density decreased | 233.1 |
| Purpura | 220.8 |
| Oral herpes | 196.0 |
| Hyperlipidaemia | 195.8 |
| Skin disorder | 183.7 |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Palmidrol is on its molecule page.
| Molecular formula | C18H37NO2 |
|---|---|
| Molecular weight | 299.50 g/mol |
| CAS number | — |
| InChIKey | HXYVTAGFYLMHSO-UHFFFAOYSA-N |
| PubChem CID | 4671 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
How does Palmidrol work?
Its molecular targets in DrugCentral include GPR55 (agonist), CNR1, CNR2 and Faah.
What is the chemical formula of Palmidrol?
Palmidrol has the molecular formula C18H37NO2 and a molecular weight of 299.50 g/mol.
Browse: all drugs starting with P · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 2045 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL417675 — compound record and bioactivity
- PubChem CID 4671 — chemical identifiers
- DrugBank DB14043 — drug record
- FDA UNII 6R8T1UDM3V — substance identity
- UniProt Q9Y2T6 (GPR55) — target protein
- UniProt P21554 (CNR1) — target protein
- UniProt P34972 (CNR2) — target protein
- FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral
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