Phenindione

BLOOD AND BLOOD FORMING ORGANS

Key facts

Phenindione is an ofm drug catalogued in DrugCentral. DrugCentral lists 3 molecular targets, including Alox5, VKORC1 and F2.

• Approval status: ofm.
• Molecular targets: Alox5, VKORC1 and F2 (3 listed in DrugCentral).
• ATC code: B01AA02 (Vitamin K antagonists).
• Molecular formula: C15H10O2; molecular weight 222.24 g/mol.

Mechanism & targets

Molecular targets (3)

Target	Gene	Action	Activity
Arachidonate 5-lipoxygenase	Alox5	unknown	IC50 4.82
Vitamin K epoxide reductase complex subunit 1	VKORC1	inhibitor	—
Prothrombin	F2	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	SANOFI AVENTIS US

ATC classification

ATC code	Therapeutic hierarchy
B01AA02	BLOOD AND BLOOD FORMING ORGANS › ANTITHROMBOTIC AGENTS › ANTITHROMBOTIC AGENTS › Vitamin K antagonists

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Phenindione is on its molecule page.

• Molecular formula: C₁₅H₁₀O₂
• Molecular weight: 222.24 g/mol
• CAS number: 83-12-5
• InChIKey: NFBAXHOPROOJAW-UHFFFAOYSA-N
• PubChem CID: 4760

O=C1C(C(=O)C2=C1C=CC=C2)C1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Phenindione work?

Its molecular targets in DrugCentral include Alox5, VKORC1 (inhibitor) and F2.

What is the chemical formula of Phenindione?

Phenindione has the molecular formula C15H10O2 and a molecular weight of 222.24 g/mol.

Sources

• DrugCentral drug card 2130 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL711 — compound record and bioactivity
• PubChem CID 4760 — chemical identifiers
• DrugBank DB00498 — drug record
• FDA UNII 5M7Y6274ZE — substance identity
• DailyMed: FDA labels for Phenindione — current prescribing information (label search)
• UniProt Q9BQB6 (VKORC1) — target protein
• UniProt P00734 (F2) — target protein

How this page is built: methodology · editorial policy & corrections.