Protionamide

ANTIINFECTIVES FOR SYSTEMIC USE

Key facts

Protionamide is a drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including PPO2.

• Molecular targets: PPO2 (1 listed in DrugCentral).
• ATC code: J04AD01 (Thiocarbamide derivatives).
• Molecular formula: C9H12N2S; molecular weight 180.28 g/mol.

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Polyphenol oxidase 2	PPO2	unknown	IC50 5.35

ATC classification

ATC code	Therapeutic hierarchy
J04AD01	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIMYCOBACTERIALS › DRUGS FOR TREATMENT OF TUBERCULOSIS › Thiocarbamide derivatives
J04AM10	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIMYCOBACTERIALS › DRUGS FOR TREATMENT OF TUBERCULOSIS › Combinations of drugs for treatment of tuberculosis
J04AM11	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIMYCOBACTERIALS › DRUGS FOR TREATMENT OF TUBERCULOSIS › Combinations of drugs for treatment of tuberculosis

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Electrocardiogram QT prolonged	324.5
Hepatotoxicity	306.6
Drug resistance	126.0
Neuropathy peripheral	96.4
Paradoxical drug reaction	50.3
Aspartate aminotransferase increased	45.9
Helicobacter gastritis	44.4

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Protionamide is on its molecule page.

• Molecular formula: C₉H₁₂N₂S
• Molecular weight: 180.28 g/mol
• CAS number: —
• InChIKey: VRDIULHPQTYCLN-UHFFFAOYSA-N
• PubChem CID: 666418

CCCC1=CC(=CC=N1)C(N)=S

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Protionamide work?

Its molecular targets in DrugCentral include PPO2.

What is the chemical formula of Protionamide?

Protionamide has the molecular formula C9H12N2S and a molecular weight of 180.28 g/mol.

Sources

• DrugCentral drug card 2314 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1378024 — compound record and bioactivity
• PubChem CID 666418 — chemical identifiers
• DrugBank DB12667 — drug record
• FDA UNII 76YOO33643 — substance identity
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.