Sepetaprost

Drug profile

Key facts

Sepetaprost is a drug catalogued in DrugCentral. It was first approved by the PMDA in 2025. DrugCentral lists 2 molecular targets, including PTGFR and PTGER3. Recorded indications include Glaucoma.

• Molecular targets: PTGFR and PTGER3 (2 listed in DrugCentral).
• Indications: Glaucoma.
• Molecular formula: C26H36F2O6; molecular weight 482.56 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Glaucoma

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Prostaglandin F2-alpha receptor	PTGFR	agonist	EC50 7.65
Prostaglandin E2 receptor EP3 subtype	PTGER3	agonist	EC50 7.54

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
2025-08-25	PMDA	—	Santen Pharmaceutical Co., Ltd.

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Sepetaprost is on its molecule page.

• Molecular formula: C₂₆H₃₆F₂O₆
• Molecular weight: 482.56 g/mol
• CAS number: —
• InChIKey: BKVUSNOUTQMSBE-XCMGCKIWSA-N
• PubChem CID: 50902259

CC(C)OC(=O)CCC[C@H]1CC[C@H]2[C@H](C[C@H]([C@@H]2/C=C/[C@H](COC3=C(C=CC(=C3)F)F)O)O)OC1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Sepetaprost used for?

DrugCentral lists the following indications for Sepetaprost: Glaucoma.

How does Sepetaprost work?

Its molecular targets in DrugCentral include PTGFR (agonist) and PTGER3 (agonist).

When was Sepetaprost first approved?

Sepetaprost was first approved by the PMDA in 2025.

What is the chemical formula of Sepetaprost?

Sepetaprost has the molecular formula C26H36F2O6 and a molecular weight of 482.56 g/mol.

Sources

• DrugCentral drug card 5805 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL4297633 — compound record and bioactivity
• PubChem CID 50902259 — chemical identifiers
• DrugBank DB12043 — drug record
• FDA UNII 79O7855J4G — substance identity
• UniProt P43088 (PTGFR) — target protein
• UniProt P43115 (PTGER3) — target protein

How this page is built: methodology · editorial policy & corrections.