Sulfapyridine

ANTIINFECTIVES FOR SYSTEMIC USE

Key facts

Sulfapyridine is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1939. DrugCentral lists 2 molecular targets, including folP and sulI. Recorded indications include Dermatitis herpetiformis.

• Approval status: ofm (first approved 1939 by the FDA).
• Molecular targets: folP and sulI (2 listed in DrugCentral).
• Indications: Dermatitis herpetiformis.
• ATC code: J01EB04 (Short-acting sulfonamides).
• Molecular formula: C11H11N3O2S; molecular weight 249.29 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Dermatitis herpetiformis

Off-label uses (3)

• Pemphigoid
• Pyoderma gangrenosum
• Subcorneal pustular dermatosis

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Dihydropteroate synthase	folP	inhibitor	—
Dihydropteroate synthase type-1	sulI	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1939-03-09	FDA	—	LILLY

ATC classification

ATC code	Therapeutic hierarchy
J01EB04	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIBACTERIALS FOR SYSTEMIC USE › SULFONAMIDES AND TRIMETHOPRIM › Short-acting sulfonamides

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Sulfapyridine is on its molecule page.

• Molecular formula: C₁₁H₁₁N₃O₂S
• Molecular weight: 249.29 g/mol
• CAS number: 144-83-2
• InChIKey: GECHUMIMRBOMGK-UHFFFAOYSA-N
• PubChem CID: 5336

NC1=CC=C(C=C1)S(=O)(=O)NC1=CC=CC=N1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Sulfapyridine used for?

DrugCentral lists the following indications for Sulfapyridine: Dermatitis herpetiformis.

How does Sulfapyridine work?

Its molecular targets in DrugCentral include folP (inhibitor) and sulI.

When was Sulfapyridine first approved?

Sulfapyridine was first approved by the FDA in 1939.

What is the chemical formula of Sulfapyridine?

Sulfapyridine has the molecular formula C11H11N3O2S and a molecular weight of 249.29 g/mol.

Sources

• DrugCentral drug card 2524 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL700 — compound record and bioactivity
• PubChem CID 5336 — chemical identifiers
• DrugBank DB00891 — drug record
• FDA UNII Y5V2N1KE8U — substance identity
• DailyMed: FDA labels for Sulfapyridine — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.