Sulfisomidine

ANTIINFECTIVES FOR SYSTEMIC USE

Key facts

Sulfisomidine is a drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including AGO2.

• Molecular targets: AGO2 (1 listed in DrugCentral).
• ATC code: J01EB01 (Short-acting sulfonamides).
• Molecular formula: C12H14N4O2S; molecular weight 278.33 g/mol.

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Protein argonaute-2	AGO2	unknown	Kd 5.37

ATC classification

ATC code	Therapeutic hierarchy
J01EB01	ANTIINFECTIVES FOR SYSTEMIC USE › ANTIBACTERIALS FOR SYSTEMIC USE › SULFONAMIDES AND TRIMETHOPRIM › Short-acting sulfonamides

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Joint dislocation	286.8
Hypercholesterolaemia	269.9
Joint stiffness	217.8
Hepatic cirrhosis	197.5
Seronegative arthritis	189.4
Anti-cyclic citrullinated peptide antibody	186.2
Grip strength decreased	175.9
Hip arthroplasty	160.4
Prescribed underdose	159.3
Lupus vulgaris	159.0
Joint range of motion decreased	157.3
Adjustment disorder with depressed mood	155.7

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Sulfisomidine is on its molecule page.

• Molecular formula: C₁₂H₁₄N₄O₂S
• Molecular weight: 278.33 g/mol
• CAS number: 515-64-0
• InChIKey: YZMCKZRAOLZXAZ-UHFFFAOYSA-N
• PubChem CID: 5343

CC1=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC(C)=N1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Sulfisomidine work?

Its molecular targets in DrugCentral include AGO2.

What is the chemical formula of Sulfisomidine?

Sulfisomidine has the molecular formula C12H14N4O2S and a molecular weight of 278.33 g/mol.

Sources

• DrugCentral drug card 2526 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL485696 — compound record and bioactivity
• PubChem CID 5343 — chemical identifiers
• DrugBank DB13283 — drug record
• FDA UNII W03L3ODK6E — substance identity
• UniProt Q9UKV8 (AGO2) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.