5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide

C7H8ClF2NO3S2 — CID 104858721

IUPAC5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide
SMILESO=S(=O)(NCC(F)(F)CO)c1ccc(Cl)s1
InChIInChI=1S/C7H8ClF2NO3S2/c8-5-1-2-6(15-5)16(13,14)11-3-7(9,10)4-12/h1-2,11-12H,3-4H2
InChIKeyLAFGIVBQGKZVRV-UHFFFAOYSA-N
MW291.73 g/mol
LogP1.31
Rot. Bonds5

About 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide

5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide (PubChem CID 104858721) has the molecular formula C7H8ClF2NO3S2 and a molecular weight of 291.73 g/mol. Its IUPAC name is 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide.

Molecular Properties

Compound Name5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide
PubChem CID104858721
Molecular FormulaC7H8ClF2NO3S2
Molecular Weight291.73 g/mol
Exact Mass290.96
IUPAC Name5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide
SMILESO=S(=O)(NCC(F)(F)CO)c1ccc(Cl)s1
InChIInChI=1S/C7H8ClF2NO3S2/c8-5-1-2-6(15-5)16(13,14)11-3-7(9,10)4-12/h1-2,11-12H,3-4H2
InChIKeyLAFGIVBQGKZVRV-UHFFFAOYSA-N
XLogP1.31
TPSA66.40 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds5
Heavy Atoms16
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500291.73
LogP ≤ 51.31
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Analyze 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

5-cyano-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide
CID 114166516
3-[(5-chlorothiophen-2-yl)sulfonylamino]-2-hydroxypropanamide
CID 107258327
ethyl (2S)-3-[(5-chlorothiophen-2-yl)sulfonylamino]-2-hydroxy-2-methylpropanoate
CID 97307644
4-amino-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide
CID 106165593
5-chloro-N-[(2-hydroxyphenyl)methyl]thiophene-2-sulfonamide
CID 113317167
4-[[(5-chlorothiophen-2-yl)sulfonylamino]methyl]benzoic acid
CID 43235820
5-chloro-N-(5,5,5-trifluoro-1-hydroxy-3-methylpentan-2-yl)thiophene-2-sulfonamide
CID 72786260
2-chloro-N-(2,2-difluoro-3-hydroxypropyl)-4-methyl-1,3-thiazole-5-sulfonamide
CID 104858839
3-[(2,2-difluoro-3-hydroxypropyl)sulfamoyl]thiophene-2-carboxylic acid
CID 114153141
5-chloro-N-[(2R)-2-(2-fluorophenyl)-2-methoxypropyl]thiophene-2-sulfonamide
CID 97428450
5-chloro-N-[4-(trifluoromethylsulfonyl)phenyl]thiophene-2-sulfonamide
CID 166200870
5-chloro-N-[2-(2-hydroxyethyl)pentyl]thiophene-2-sulfonamide
CID 103836355

Frequently Asked Questions

What is the IUPAC name of 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide?
The IUPAC name of 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide (CID 104858721) is 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide.
What is the SMILES notation for 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide?
The canonical SMILES for 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide is O=S(=O)(NCC(F)(F)CO)c1ccc(Cl)s1.
What is the InChIKey of 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide?
The InChIKey is LAFGIVBQGKZVRV-UHFFFAOYSA-N. The full InChI is InChI=1S/C7H8ClF2NO3S2/c8-5-1-2-6(15-5)16(13,14)11-3-7(9,10)4-12/h1-2,11-12H,3-4H2.
What are the key properties of 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide?
5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide has a molecular weight of 291.73 g/mol, XLogP of 1.31, 5 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-N-(2,2-difluoro-3-hydroxypropyl)thiophene-2-sulfonamide is sourced from PubChem (CID 104858721), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).