3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide

C16H18N2O4S2 — CID 108562969

IUPAC3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide
SMILESO=C(NC1CCN(S(=O)(=O)c2cccs2)CC1)c1cccc(O)c1
InChIInChI=1S/C16H18N2O4S2/c19-14-4-1-3-12(11-14)16(20)17-13-6-8-18(9-7-13)24(21,22)15-5-2-10-23-15/h1-5,10-11,13,19H,6-9H2,(H,17,20)
InChIKeySRVHBNGZNUHLMU-UHFFFAOYSA-N
MW366.46 g/mol
LogP2.04
Rot. Bonds4

About 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide

3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide (PubChem CID 108562969) has the molecular formula C16H18N2O4S2 and a molecular weight of 366.46 g/mol. Its IUPAC name is 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide.

Molecular Properties

Compound Name3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide
PubChem CID108562969
Molecular FormulaC16H18N2O4S2
Molecular Weight366.46 g/mol
Exact Mass366.07
IUPAC Name3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide
SMILESO=C(NC1CCN(S(=O)(=O)c2cccs2)CC1)c1cccc(O)c1
InChIInChI=1S/C16H18N2O4S2/c19-14-4-1-3-12(11-14)16(20)17-13-6-8-18(9-7-13)24(21,22)15-5-2-10-23-15/h1-5,10-11,13,19H,6-9H2,(H,17,20)
InChIKeySRVHBNGZNUHLMU-UHFFFAOYSA-N
XLogP2.04
TPSA86.71 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds4
Heavy Atoms24
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500366.46
LogP ≤ 52.04
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

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Related Compounds

[3-[(1-thiophen-2-ylsulfonylpiperidin-4-yl)carbamoyl]phenyl] acetate
CID 108559053
4-fluoro-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide
CID 35400940
3-hydroxy-N-[1-(4-methylphenyl)sulfonylpiperidin-4-yl]benzamide
CID 108562939
2,5-dichloro-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide
CID 108561586
2-phenyl-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)acetamide
CID 108560111
ethyl [4-[(1-thiophen-2-ylsulfonylpiperidin-4-yl)carbamoyl]phenyl] carbonate
CID 108559085
2,2-diphenyl-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)acetamide
CID 108559458
1-tert-butyl-3-(1-thiophen-2-ylsulfonylpiperidin-4-yl)urea
CID 110823258
2-ethyl-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)butanamide
CID 110823252
2-[(1-thiophen-2-ylsulfonylpiperidin-4-yl)amino]phenol
CID 141034176
5-(furan-2-yl)-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)-1H-pyrazole-3-carboxamide
CID 167798179
3-hydroxy-N-[1-(3-methoxybenzoyl)piperidin-4-yl]benzamide
CID 108558264

Frequently Asked Questions

What is the IUPAC name of 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide?
The IUPAC name of 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide (CID 108562969) is 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide.
What is the SMILES notation for 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide?
The canonical SMILES for 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide is O=C(NC1CCN(S(=O)(=O)c2cccs2)CC1)c1cccc(O)c1.
What is the InChIKey of 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide?
The InChIKey is SRVHBNGZNUHLMU-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H18N2O4S2/c19-14-4-1-3-12(11-14)16(20)17-13-6-8-18(9-7-13)24(21,22)15-5-2-10-23-15/h1-5,10-11,13,19H,6-9H2,(H,17,20).
What are the key properties of 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide?
3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide has a molecular weight of 366.46 g/mol, XLogP of 2.04, 4 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 3-hydroxy-N-(1-thiophen-2-ylsulfonylpiperidin-4-yl)benzamide is sourced from PubChem (CID 108562969), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).