N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide

C24H24F2N4O4 — CID 118366455

IUPACN-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide
SMILESCC(=O)NCc1ncccc1-c1ccc(C(=O)CN2C(=O)NC3(CCC(F)(F)CC3)C2=O)cc1
InChIInChI=1S/C24H24F2N4O4/c1-15(31)28-13-19-18(3-2-12-27-19)16-4-6-17(7-5-16)20(32)14-30-21(33)23(29-22(30)34)8-10-24(25,26)11-9-23/h2-7,12H,8-11,13-14H2,1H3,(H,28,31)(H,29,34)
InChIKeyMENWCIZVXAFACY-UHFFFAOYSA-N
MW470.48 g/mol
LogP3.07
Rot. Bonds6

About N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide

N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide (PubChem CID 118366455) has the molecular formula C24H24F2N4O4 and a molecular weight of 470.48 g/mol. Its IUPAC name is N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide.

Molecular Properties

Compound NameN-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide
PubChem CID118366455
Molecular FormulaC24H24F2N4O4
Molecular Weight470.48 g/mol
Exact Mass470.18
IUPAC NameN-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide
SMILESCC(=O)NCc1ncccc1-c1ccc(C(=O)CN2C(=O)NC3(CCC(F)(F)CC3)C2=O)cc1
InChIInChI=1S/C24H24F2N4O4/c1-15(31)28-13-19-18(3-2-12-27-19)16-4-6-17(7-5-16)20(32)14-30-21(33)23(29-22(30)34)8-10-24(25,26)11-9-23/h2-7,12H,8-11,13-14H2,1H3,(H,28,31)(H,29,34)
InChIKeyMENWCIZVXAFACY-UHFFFAOYSA-N
XLogP3.07
TPSA108.47 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds6
Heavy Atoms34
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500470.48
LogP ≤ 53.07
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'hydantoin', 'substructure': 'N/A'}

Analyze N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

8,8-difluoro-3-[2-[4-[3-(hydroxymethyl)-2-pyridinyl]phenyl]-2-oxoethyl]-1,3-diazaspiro[4.5]decane-2,4-dione
CID 118366358
8,8-difluoro-3-[2-oxo-2-[4-(1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]ethyl]-1,3-diazaspiro[4.5]decane-2,4-dione
CID 118366425
8,8-difluoro-3-[2-(4-imidazo[1,2-b]pyridazin-3-ylphenyl)-2-oxoethyl]-1,3-diazaspiro[4.5]decane-2,4-dione
CID 118366350
3-[2-[4-[(3-amino-2-pyridinyl)amino]phenyl]-2-oxoethyl]-8,8-difluoro-4-methylidene-1,3-diazaspiro[4.5]decan-2-one
CID 155274461
N-[2-[4-[2-(2,4-dioxo-1,3-diazaspiro[4.6]undecan-3-yl)acetyl]-2-fluorophenyl]ethyl]acetamide
CID 46483879
6-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenoxy]pyridine-2-carbonitrile
CID 118366430
N-[[4-[2-[(4S)-4-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]acetyl]phenyl]methyl]acetamide
CID 40764733
8,8-difluoro-3-[2-[5-(3-fluorophenyl)-1-methylimidazol-2-yl]-2-oxoethyl]-1,3-diazaspiro[4.5]decane-2,4-dione
CID 118366506
3-[2-(4-bromophenyl)-2-oxoethyl]-1,3-diazaspiro[4.6]undecane-2,4-dione
CID 2710899
N-[4-[2-(2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl)acetyl]phenyl]propanamide
CID 7277275
3-[2-[4-[(3-amino-6-methyl-2-pyridinyl)amino]phenyl]-2-oxoethyl]-8-fluoro-8-methyl-1,3-diazaspiro[4.5]decane-2,4-dione
CID 157228897
3-[2-oxo-2-(4-phenoxyphenyl)ethyl]-1,3-diazaspiro[4.7]dodecane-2,4-dione
CID 51113723

Frequently Asked Questions

What is the IUPAC name of N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide?
The IUPAC name of N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide (CID 118366455) is N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide.
What is the SMILES notation for N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide?
The canonical SMILES for N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide is CC(=O)NCc1ncccc1-c1ccc(C(=O)CN2C(=O)NC3(CCC(F)(F)CC3)C2=O)cc1.
What is the InChIKey of N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide?
The InChIKey is MENWCIZVXAFACY-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H24F2N4O4/c1-15(31)28-13-19-18(3-2-12-27-19)16-4-6-17(7-5-16)20(32)14-30-21(33)23(29-22(30)34)8-10-24(25,26)11-9-23/h2-7,12H,8-11,13-14H2,1H3,(H,28,31)(H,29,34).
What are the key properties of N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide?
N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide has a molecular weight of 470.48 g/mol, XLogP of 3.07, 6 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-[[3-[4-[2-(8,8-difluoro-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]phenyl]-2-pyridinyl]methyl]acetamide is sourced from PubChem (CID 118366455), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).