5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine

C20H14FN5O — CID 118598335

IUPAC5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine
SMILESNc1cnc(-c2ccc(-c3ccccc3Oc3ccncn3)cc2F)cn1
InChIInChI=1S/C20H14FN5O/c21-16-9-13(5-6-15(16)17-10-25-19(22)11-24-17)14-3-1-2-4-18(14)27-20-7-8-23-12-26-20/h1-12H,(H2,22,25)
InChIKeyPDBORINZHRQVQQ-UHFFFAOYSA-N
MW359.36 g/mol
LogP4.11
Rot. Bonds4

About 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine

5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine (PubChem CID 118598335) has the molecular formula C20H14FN5O and a molecular weight of 359.36 g/mol. Its IUPAC name is 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine.

Molecular Properties

Compound Name5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine
PubChem CID118598335
Molecular FormulaC20H14FN5O
Molecular Weight359.36 g/mol
Exact Mass359.12
IUPAC Name5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine
SMILESNc1cnc(-c2ccc(-c3ccccc3Oc3ccncn3)cc2F)cn1
InChIInChI=1S/C20H14FN5O/c21-16-9-13(5-6-15(16)17-10-25-19(22)11-24-17)14-3-1-2-4-18(14)27-20-7-8-23-12-26-20/h1-12H,(H2,22,25)
InChIKeyPDBORINZHRQVQQ-UHFFFAOYSA-N
XLogP4.11
TPSA86.81 Ų
H-Bond Donors1
H-Bond Acceptors6
Rotatable Bonds4
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500359.36
LogP ≤ 54.11
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 106

Analyze 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6-[2-[4-(5-aminopyrazin-2-yl)-3-fluorophenyl]phenyl]sulfanylpyrimidin-4-amine
CID 90313818
5-[4-[2-(6-aminopyrazin-2-yl)sulfanylphenyl]-2-fluorophenyl]pyrazin-2-amine
CID 90314307
5-[2-fluoro-4-[2-methoxy-4-(trifluoromethyl)phenyl]phenyl]pyrazin-2-amine
CID 90313982
N-(2-aminoethyl)-2-[4-(5-aminopyrazin-2-yl)-3-fluorophenyl]benzenesulfinamide
CID 138711929
5-[2-fluoro-4-[2-(pyrimidin-2-ylsulfinylmethyl)phenyl]phenyl]pyrazin-2-amine
CID 137396074
5-[2-fluoro-4-(2-pyrimidin-2-yloxyphenyl)phenyl]pyrimidin-2-amine
CID 90314938
2-[4-(5-aminopyrazin-2-yl)-3-fluorophenyl]-N-pyridin-3-ylbenzenesulfinamide
CID 138711674
N-[2-[4-(5-aminopyrazin-2-yl)-3-fluorophenyl]phenyl]benzenesulfonamide
CID 90313395
5-[2-fluoro-4-[2-(propan-2-ylsulfanylmethyl)phenyl]phenyl]pyrazin-2-amine;hydrochloride
CID 90312683
5-[2-fluoro-4-[2-(oxan-4-ylmethylsulfinyl)-3-pyridinyl]phenyl]pyrazin-2-amine
CID 137396065
5-[4-(2-amino-5-methylphenyl)-2-fluorophenyl]pyrazin-2-amine
CID 144679153
1-[2-[4-(5-aminopyrazin-2-yl)-3-fluorophenyl]phenyl]sulfonylpyrrolidine-3,4-diol
CID 90314151

Frequently Asked Questions

What is the IUPAC name of 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine?
The IUPAC name of 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine (CID 118598335) is 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine.
What is the SMILES notation for 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine?
The canonical SMILES for 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine is Nc1cnc(-c2ccc(-c3ccccc3Oc3ccncn3)cc2F)cn1.
What is the InChIKey of 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine?
The InChIKey is PDBORINZHRQVQQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H14FN5O/c21-16-9-13(5-6-15(16)17-10-25-19(22)11-24-17)14-3-1-2-4-18(14)27-20-7-8-23-12-26-20/h1-12H,(H2,22,25).
What are the key properties of 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine?
5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine has a molecular weight of 359.36 g/mol, XLogP of 4.11, 4 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[2-fluoro-4-(2-pyrimidin-4-yloxyphenyl)phenyl]pyrazin-2-amine is sourced from PubChem (CID 118598335), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).