2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide

C8H7ClF2N2O — CID 119018698

IUPAC2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide
SMILESCc1nc(Cl)c(C(N)=O)cc1C(F)F
InChIInChI=1S/C8H7ClF2N2O/c1-3-4(7(10)11)2-5(8(12)14)6(9)13-3/h2,7H,1H3,(H2,12,14)
InChIKeyNUFWFJAXEMHEEH-UHFFFAOYSA-N
MW220.61 g/mol
LogP2.08
Rot. Bonds2

About 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide

2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide (PubChem CID 119018698) has the molecular formula C8H7ClF2N2O and a molecular weight of 220.61 g/mol. Its IUPAC name is 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide.

Molecular Properties

Compound Name2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide
PubChem CID119018698
Molecular FormulaC8H7ClF2N2O
Molecular Weight220.61 g/mol
Exact Mass220.02
IUPAC Name2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide
SMILESCc1nc(Cl)c(C(N)=O)cc1C(F)F
InChIInChI=1S/C8H7ClF2N2O/c1-3-4(7(10)11)2-5(8(12)14)6(9)13-3/h2,7H,1H3,(H2,12,14)
InChIKeyNUFWFJAXEMHEEH-UHFFFAOYSA-N
XLogP2.08
TPSA55.98 Ų
H-Bond Donors1
H-Bond Acceptors2
Rotatable Bonds2
Heavy Atoms14
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500220.61
LogP ≤ 52.08
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 102

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Analyze 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

methyl 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxylate
CID 130074421
2-chloro-6-(difluoromethyl)-5-fluoropyridine-3-carboxamide
CID 119016340
5-(difluoromethyl)-2-iodo-6-methylpyridine-3-carbonyl chloride
CID 130086388
6-chloro-4-(difluoromethyl)-5-methylpyridine-2-carboxamide
CID 118990312
ethyl 2-[6-chloro-5-(difluoromethyl)-2-methyl-3-pyridinyl]acetate
CID 134674085
6-chloro-3-(difluoromethyl)-5-methoxypyridine-2-carboxamide
CID 119005525
ethyl 6-chloro-2-(chloromethyl)-5-(difluoromethyl)pyridine-3-carboxylate
CID 134674225
6-(difluoromethyl)-5-hydroxy-2-methylpyridine-3-carboxamide
CID 118837404
methyl 2-(chloromethyl)-5-(difluoromethyl)-6-methylpyridine-3-carboxylate
CID 130090555
methyl 2-(aminomethyl)-5-(difluoromethyl)-6-methylpyridine-3-carboxylate
CID 133098700
4-(difluoromethyl)-5-fluoro-6-methylpyridine-2-carboxamide
CID 118851932
5-(difluoromethyl)-6-iodo-2-methylpyridine-3-carbonyl chloride
CID 130086366

Frequently Asked Questions

What is the IUPAC name of 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide?
The IUPAC name of 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide (CID 119018698) is 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide.
What is the SMILES notation for 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide?
The canonical SMILES for 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide is Cc1nc(Cl)c(C(N)=O)cc1C(F)F.
What is the InChIKey of 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide?
The InChIKey is NUFWFJAXEMHEEH-UHFFFAOYSA-N. The full InChI is InChI=1S/C8H7ClF2N2O/c1-3-4(7(10)11)2-5(8(12)14)6(9)13-3/h2,7H,1H3,(H2,12,14).
What are the key properties of 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide?
2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide has a molecular weight of 220.61 g/mol, XLogP of 2.08, 2 rotatable bonds, 1 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 2-chloro-5-(difluoromethyl)-6-methylpyridine-3-carboxamide is sourced from PubChem (CID 119018698), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).