2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine

C11H15F2N3 — CID 129493941

IUPAC2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine
SMILESNc1cccnc1N1CCC[C@@H](C(F)F)C1
InChIInChI=1S/C11H15F2N3/c12-10(13)8-3-2-6-16(7-8)11-9(14)4-1-5-15-11/h1,4-5,8,10H,2-3,6-7,14H2/t8-/m1/s1
InChIKeyAJKOYUFWPFECKJ-MRVPVSSYSA-N
MW227.26 g/mol
LogP2.15
Rot. Bonds2

About 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine

2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine (PubChem CID 129493941) has the molecular formula C11H15F2N3 and a molecular weight of 227.26 g/mol. Its IUPAC name is 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine.

Molecular Properties

Compound Name2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine
PubChem CID129493941
Molecular FormulaC11H15F2N3
Molecular Weight227.26 g/mol
Exact Mass227.12
IUPAC Name2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine
SMILESNc1cccnc1N1CCC[C@@H](C(F)F)C1
InChIInChI=1S/C11H15F2N3/c12-10(13)8-3-2-6-16(7-8)11-9(14)4-1-5-15-11/h1,4-5,8,10H,2-3,6-7,14H2/t8-/m1/s1
InChIKeyAJKOYUFWPFECKJ-MRVPVSSYSA-N
XLogP2.15
TPSA42.15 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms16
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500227.26
LogP ≤ 52.15
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

2-[(3S)-3-(difluoromethyl)pyrrolidin-1-yl]pyridin-3-amine
CID 129498833
2-chloro-3-[(3S)-3-(difluoromethyl)piperidin-1-yl]pyrazine
CID 129498626
2-(azocan-1-yl)pyridin-3-amine
CID 28799710
2-[3-(difluoromethyl)pyrrolidin-1-yl]pyridine-3-carboxylic acid
CID 121201168
2-[(3R)-3-(difluoromethyl)pyrrolidin-1-yl]pyridine-3-carboxylic acid
CID 129499940
(3R,4R)-1-(3-amino-2-pyridinyl)-3-methylpiperidin-4-ol
CID 129445700
2-[3-(difluoromethyl)pyrrolidin-1-yl]-3-ethylsulfonylpyridine
CID 154780352
2-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)pyridin-3-amine
CID 66391110
2-(4-methyl-1,4-diazepan-1-yl)pyridin-3-amine
CID 28744763
2-chloro-3-[(3S)-3-(difluoromethyl)pyrrolidin-1-yl]pyrazine
CID 129499164
[2-[4-(difluoromethyl)piperidin-1-yl]-3-pyridinyl]methanamine
CID 175948489
2-(3,4-dimethoxypyrrolidin-1-yl)pyridin-3-amine
CID 103530537

Frequently Asked Questions

What is the IUPAC name of 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine?
The IUPAC name of 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine (CID 129493941) is 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine.
What is the SMILES notation for 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine?
The canonical SMILES for 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine is Nc1cccnc1N1CCC[C@@H](C(F)F)C1.
What is the InChIKey of 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine?
The InChIKey is AJKOYUFWPFECKJ-MRVPVSSYSA-N. The full InChI is InChI=1S/C11H15F2N3/c12-10(13)8-3-2-6-16(7-8)11-9(14)4-1-5-15-11/h1,4-5,8,10H,2-3,6-7,14H2/t8-/m1/s1.
What are the key properties of 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine?
2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine has a molecular weight of 227.26 g/mol, XLogP of 2.15, 2 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[(3R)-3-(difluoromethyl)piperidin-1-yl]pyridin-3-amine is sourced from PubChem (CID 129493941), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).