5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol

C8H6F5NO3 — CID 134660021

IUPAC5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol
SMILESOCc1nc(OC(F)(F)F)c(O)cc1C(F)F
InChIInChI=1S/C8H6F5NO3/c9-6(10)3-1-5(16)7(14-4(3)2-15)17-8(11,12)13/h1,6,15-16H,2H2
InChIKeyUNCMHOCEGSRVKP-UHFFFAOYSA-N
MW259.13 g/mol
LogP2.12
Rot. Bonds3

About 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol

5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol (PubChem CID 134660021) has the molecular formula C8H6F5NO3 and a molecular weight of 259.13 g/mol. Its IUPAC name is 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol.

Molecular Properties

Compound Name5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol
PubChem CID134660021
Molecular FormulaC8H6F5NO3
Molecular Weight259.13 g/mol
Exact Mass259.03
IUPAC Name5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol
SMILESOCc1nc(OC(F)(F)F)c(O)cc1C(F)F
InChIInChI=1S/C8H6F5NO3/c9-6(10)3-1-5(16)7(14-4(3)2-15)17-8(11,12)13/h1,6,15-16H,2H2
InChIKeyUNCMHOCEGSRVKP-UHFFFAOYSA-N
XLogP2.12
TPSA62.58 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds3
Heavy Atoms17
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500259.13
LogP ≤ 52.12
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Analyze 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

6-(aminomethyl)-5-(difluoromethyl)-2-(trifluoromethoxy)pyridin-3-ol
CID 118808647
[5-(difluoromethyl)-3-nitro-6-(trifluoromethoxy)-2-pyridinyl]methanol
CID 134678877
[5-bromo-3-(difluoromethyl)-6-methoxy-2-pyridinyl]methanol
CID 130068911
[6-amino-5-(difluoromethyl)-3-(trifluoromethoxy)-2-pyridinyl]methanol
CID 119008282
[4-(difluoromethyl)-6-iodo-2-(trifluoromethoxy)-3-pyridinyl]methanol
CID 118829537
[5-(difluoromethyl)-6-iodo-2-(trifluoromethoxy)-3-pyridinyl]methanol
CID 134662929
methyl 6-(chloromethyl)-5-(difluoromethyl)-2-(trifluoromethoxy)pyridine-3-carboxylate
CID 134668977
6-(aminomethyl)-2-(trifluoromethoxy)-5-(trifluoromethyl)pyridin-3-ol
CID 134680204
6-(aminomethyl)-5-(difluoromethyl)-2-(trifluoromethoxy)pyridine-3-carbonyl chloride
CID 118808665
[5-(difluoromethyl)-6-methoxy-3-(trifluoromethyl)-2-pyridinyl]methanol
CID 133099748
6-chloro-5-(difluoromethyl)-2-(hydroxymethyl)pyridin-3-ol
CID 119001935
2-[5-hydroxy-3-iodo-6-(trifluoromethoxy)-2-pyridinyl]acetic acid
CID 134680320

Frequently Asked Questions

What is the IUPAC name of 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol?
The IUPAC name of 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol (CID 134660021) is 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol.
What is the SMILES notation for 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol?
The canonical SMILES for 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol is OCc1nc(OC(F)(F)F)c(O)cc1C(F)F.
What is the InChIKey of 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol?
The InChIKey is UNCMHOCEGSRVKP-UHFFFAOYSA-N. The full InChI is InChI=1S/C8H6F5NO3/c9-6(10)3-1-5(16)7(14-4(3)2-15)17-8(11,12)13/h1,6,15-16H,2H2.
What are the key properties of 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol?
5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol has a molecular weight of 259.13 g/mol, XLogP of 2.12, 3 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(difluoromethyl)-6-(hydroxymethyl)-2-(trifluoromethoxy)pyridin-3-ol is sourced from PubChem (CID 134660021), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).