6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide

C32H48N6O5Si — CID 140672975

IUPAC6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
SMILESCOC(OC)c1nc2c(cc1CO[Si](C)(C)C(C)(C)C)CCCN2C(=O)Nc1cc(OCC2CCCCN2C)c(C#N)cn1
InChIInChI=1S/C32H48N6O5Si/c1-32(2,3)44(7,8)43-20-23-16-22-12-11-15-38(29(22)36-28(23)30(40-5)41-6)31(39)35-27-17-26(24(18-33)19-34-27)42-21-25-13-9-10-14-37(25)4/h16-17,19,25,30H,9-15,20-21H2,1-8H3,(H,34,35,39)
InChIKeyCNBQYIILBXHOLK-UHFFFAOYSA-N
MW624.86 g/mol
LogP6.01
Rot. Bonds10

About 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide

6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide (PubChem CID 140672975) has the molecular formula C32H48N6O5Si and a molecular weight of 624.86 g/mol. Its IUPAC name is 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide.

Molecular Properties

Compound Name6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
PubChem CID140672975
Molecular FormulaC32H48N6O5Si
Molecular Weight624.86 g/mol
Exact Mass624.35
IUPAC Name6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
SMILESCOC(OC)c1nc2c(cc1CO[Si](C)(C)C(C)(C)C)CCCN2C(=O)Nc1cc(OCC2CCCCN2C)c(C#N)cn1
InChIInChI=1S/C32H48N6O5Si/c1-32(2,3)44(7,8)43-20-23-16-22-12-11-15-38(29(22)36-28(23)30(40-5)41-6)31(39)35-27-17-26(24(18-33)19-34-27)42-21-25-13-9-10-14-37(25)4/h16-17,19,25,30H,9-15,20-21H2,1-8H3,(H,34,35,39)
InChIKeyCNBQYIILBXHOLK-UHFFFAOYSA-N
XLogP6.01
TPSA122.07 Ų
H-Bond Donors1
H-Bond Acceptors9
Rotatable Bonds10
Heavy Atoms44
Complexity—

Lipinski Rule of Five

2 violations

RuleValue
MW ≤ 500624.86
LogP ≤ 56.01
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 109

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'heavy_metal', 'substructure': 'N/A'}, {'alert_name': 'het-C-het_not_in_ring', 'substructure': 'N/A'}

Analyze 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide?
The IUPAC name of 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide (CID 140672975) is 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide.
What is the SMILES notation for 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide?
The canonical SMILES for 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide is COC(OC)c1nc2c(cc1CO[Si](C)(C)C(C)(C)C)CCCN2C(=O)Nc1cc(OCC2CCCCN2C)c(C#N)cn1.
What is the InChIKey of 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide?
The InChIKey is CNBQYIILBXHOLK-UHFFFAOYSA-N. The full InChI is InChI=1S/C32H48N6O5Si/c1-32(2,3)44(7,8)43-20-23-16-22-12-11-15-38(29(22)36-28(23)30(40-5)41-6)31(39)35-27-17-26(24(18-33)19-34-27)42-21-25-13-9-10-14-37(25)4/h16-17,19,25,30H,9-15,20-21H2,1-8H3,(H,34,35,39).
What are the key properties of 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide?
6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide has a molecular weight of 624.86 g/mol, XLogP of 6.01, 10 rotatable bonds, 1 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[[tert-butyl(dimethyl)silyl]oxymethyl]-N-[5-cyano-4-[(1-methylpiperidin-2-yl)methoxy]-2-pyridinyl]-7-(dimethoxymethyl)-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide is sourced from PubChem (CID 140672975), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).