N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide

C18H17F3N2O3 — CID 146305981

IUPACN-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide
SMILESCc1cc(C2(C(F)(F)CF)CC2)ccc1Oc1ccc(C(=O)NO)cn1
InChIInChI=1S/C18H17F3N2O3/c1-11-8-13(17(6-7-17)18(20,21)10-19)3-4-14(11)26-15-5-2-12(9-22-15)16(24)23-25/h2-5,8-9,25H,6-7,10H2,1H3,(H,23,24)
InChIKeyLJIAHQOLJQKOPU-UHFFFAOYSA-N
MW366.34 g/mol
LogP3.94
Rot. Bonds6

About N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide

N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide (PubChem CID 146305981) has the molecular formula C18H17F3N2O3 and a molecular weight of 366.34 g/mol. Its IUPAC name is N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide.

Molecular Properties

Compound NameN-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide
PubChem CID146305981
Molecular FormulaC18H17F3N2O3
Molecular Weight366.34 g/mol
Exact Mass366.12
IUPAC NameN-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide
SMILESCc1cc(C2(C(F)(F)CF)CC2)ccc1Oc1ccc(C(=O)NO)cn1
InChIInChI=1S/C18H17F3N2O3/c1-11-8-13(17(6-7-17)18(20,21)10-19)3-4-14(11)26-15-5-2-12(9-22-15)16(24)23-25/h2-5,8-9,25H,6-7,10H2,1H3,(H,23,24)
InChIKeyLJIAHQOLJQKOPU-UHFFFAOYSA-N
XLogP3.94
TPSA71.45 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds6
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500366.34
LogP ≤ 53.94
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Analyze N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1-[6-[4-[1-(1,1-difluoroethyl)cyclopropyl]-2-methylphenoxy]-3-pyridinyl]ethanone
CID 158968389
ethyl 6-[2-chloro-4-[1-(trifluoromethyl)cyclopropyl]phenoxy]pyridine-3-carboxylate
CID 142415214
6-[2-fluoro-4-[1-(1,1,2,2,2-pentafluoroethyl)cyclopropyl]phenoxy]-N,N-dimethylpyridine-3-carboxamide
CID 142414873
4-[(5-fluoro-2-pyridinyl)oxy]-3-methylbenzoic acid
CID 107672839
N-hydroxy-6-[4-(trifluoromethyl)phenoxy]pyridine-3-carboxamide
CID 135313676
6-[2-fluoro-4-(1-methylcyclopropyl)phenoxy]pyridine-3-carboxylic acid
CID 157386377
1-[6-[2-fluoro-4-(1-methylcyclopropyl)phenoxy]-3-pyridinyl]-2-hydroxyethanone
CID 161152364
N-hydroxy-6-[4-(1,1,1-trifluoropropan-2-yl)phenoxy]pyridine-3-carboxamide
CID 162609023
6-[4-(2-aminoethyl)-2-methylphenoxy]pyridine-3-carboxamide
CID 59730260
6-(2,3,5-trimethylphenoxy)pyridine-3-carboxylic acid
CID 28933532
6-[(4-methyl-1-oxo-2,3-dihydroinden-5-yl)oxy]pyridine-3-carboxamide
CID 59750675
N-hydroxy-6-(4-pentylphenoxy)pyridine-3-carboxamide
CID 142415304

Frequently Asked Questions

What is the IUPAC name of N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide?
The IUPAC name of N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide (CID 146305981) is N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide.
What is the SMILES notation for N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide?
The canonical SMILES for N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide is Cc1cc(C2(C(F)(F)CF)CC2)ccc1Oc1ccc(C(=O)NO)cn1.
What is the InChIKey of N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide?
The InChIKey is LJIAHQOLJQKOPU-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H17F3N2O3/c1-11-8-13(17(6-7-17)18(20,21)10-19)3-4-14(11)26-15-5-2-12(9-22-15)16(24)23-25/h2-5,8-9,25H,6-7,10H2,1H3,(H,23,24).
What are the key properties of N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide?
N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide has a molecular weight of 366.34 g/mol, XLogP of 3.94, 6 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-hydroxy-6-[2-methyl-4-[1-(1,1,2-trifluoroethyl)cyclopropyl]phenoxy]pyridine-3-carboxamide is sourced from PubChem (CID 146305981), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).