N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide

C126H149F7N28O12S — CID 158433049

About N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide

N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide (PubChem CID 158433049) has the molecular formula C126H149F7N28O12S and a molecular weight of 2412.81 g/mol. Its IUPAC name is N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide.

Molecular Properties

• Compound Name: N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide
• PubChem CID: 158433049
• Molecular Formula: C126H149F7N28O12S
• Molecular Weight: 2412.81 g/mol
• Exact Mass: 2411.15
• IUPAC Name: N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide
• SMILES: O=C(Nc1cc(C(F)(F)CN2CCOCC2)ccc1N1CCCCC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1cc(C(F)(F)CN2CCOCC2)ccc1N1CCCCC1)c1cccc(-c2cn[nH]c2)n1.O=C(Nc1cc(CCN2CCOCC2)c(F)cc1N1CCCCC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1cc(CCN2CCOCC2)c(F)cc1N1CCCCC1)c1cccc(-c2cn[nH]c2)n1.O=C(Nc1cc(CCN2CCOCC2)c(F)cc1N1CCCCC1)c1csc(-c2cn[nH]c2)n1
• InChI: InChI=1S/C26H30F2N6O2.C26H31FN6O2.C25H29F2N5O3.C25H30FN5O3.C24H29FN6O2S/c27-26(28,18-33-11-13-36-14-12-33)20-7-8-24(34-9-2-1-3-10-34)23(15-20)32-25(35)22-6-4-5-21(31-22)19-16-29-30-17-19;27-21-16-25(33-8-2-1-3-9-33)24(15-19(21)7-10-32-11-13-35-14-12-32)31-26(34)23-6-4-5-22(30-23)20-17-28-29-18-20;26-25(27,17-31-10-12-34-13-11-31)19-4-5-21(32-8-2-1-3-9-32)20(14-19)30-24(33)23-7-6-22(35-23)18-15-28-29-16-18;26-20-15-22(31-7-2-1-3-8-31)21(14-18(20)6-9-30-10-12-33-13-11-30)29-25(32)24-5-4-23(34-24)19-16-27-28-17-19;25-19-13-22(31-5-2-1-3-6-31)20(12-17(19)4-7-30-8-10-33-11-9-30)28-23(32)21-16-34-24(29-21)18-14-26-27-15-18/h4-8,15-17H,1-3,9-14,18H2,(H,29,30)(H,32,35);4-6,15-18H,1-3,7-14H2,(H,28,29)(H,31,34);4-7,14-16H,1-3,8-13,17H2,(H,28,29)(H,30,33);4-5,14-17H,1-3,6-13H2,(H,27,28)(H,29,32);12-16H,1-11H2,(H,26,27)(H,28,32)
• InChIKey: HBWVRCDNCZHXBG-UHFFFAOYSA-N
• XLogP: 19.92
• TPSA: 432.40 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 31
• Rotatable Bonds: 35
• Heavy Atoms: 174
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2412.81
LogP ≤ 5	19.92
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	31

Frequently Asked Questions

What is the IUPAC name of N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The IUPAC name of N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide (CID 158433049) is N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide.

What is the SMILES notation for N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The canonical SMILES for N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide is O=C(Nc1cc(C(F)(F)CN2CCOCC2)ccc1N1CCCCC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1cc(C(F)(F)CN2CCOCC2)ccc1N1CCCCC1)c1cccc(-c2cn[nH]c2)n1.O=C(Nc1cc(CCN2CCOCC2)c(F)cc1N1CCCCC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1cc(CCN2CCOCC2)c(F)cc1N1CCCCC1)c1cccc(-c2cn[nH]c2)n1.O=C(Nc1cc(CCN2CCOCC2)c(F)cc1N1CCCCC1)c1csc(-c2cn[nH]c2)n1.

What is the InChIKey of N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The InChIKey is HBWVRCDNCZHXBG-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H30F2N6O2.C26H31FN6O2.C25H29F2N5O3.C25H30FN5O3.C24H29FN6O2S/c27-26(28,18-33-11-13-36-14-12-33)20-7-8-24(34-9-2-1-3-10-34)23(15-20)32-25(35)22-6-4-5-21(31-22)19-16-29-30-17-19;27-21-16-25(33-8-2-1-3-9-33)24(15-19(21)7-10-32-11-13-35-14-12-32)31-26(34)23-6-4-5-22(30-23)20-17-28-29-18-20;26-25(27,17-31-10-12-34-13-11-31)19-4-5-21(32-8-2-1-3-9-32)20(14-19)30-24(33)23-7-6-22(35-23)18-15-28-29-16-18;26-20-15-22(31-7-2-1-3-8-31)21(14-18(20)6-9-30-10-12-33-13-11-30)29-25(32)24-5-4-23(34-24)19-16-27-28-17-19;25-19-13-22(31-5-2-1-3-6-31)20(12-17(19)4-7-30-8-10-33-11-9-30)28-23(32)21-16-34-24(29-21)18-14-26-27-15-18/h4-8,15-17H,1-3,9-14,18H2,(H,29,30)(H,32,35);4-6,15-18H,1-3,7-14H2,(H,28,29)(H,31,34);4-7,14-16H,1-3,8-13,17H2,(H,28,29)(H,30,33);4-5,14-17H,1-3,6-13H2,(H,27,28)(H,29,32);12-16H,1-11H2,(H,26,27)(H,28,32).

What are the key properties of N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide has a molecular weight of 2412.81 g/mol, XLogP of 19.92, 35 rotatable bonds, 10 hydrogen bond donors, and 31 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(1,1-difluoro-2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[4-fluoro-5-(2-morpholin-4-ylethyl)-2-piperidin-1-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide is sourced from PubChem (CID 158433049), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).