N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide

C119H138F4N28O15S — CID 158491025

About N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide

N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide (PubChem CID 158491025) has the molecular formula C119H138F4N28O15S and a molecular weight of 2308.65 g/mol. Its IUPAC name is N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide.

Molecular Properties

• Compound Name: N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide
• PubChem CID: 158491025
• Molecular Formula: C119H138F4N28O15S
• Molecular Weight: 2308.65 g/mol
• Exact Mass: 2307.06
• IUPAC Name: N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide
• SMILES: CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2ccc(-c3cn[nH]c3)o2)CC1.CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2cccc(-c3cn[nH]c3)n2)CC1.CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2csc(-c3cn[nH]c3)n2)CC1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCC(F)(F)CC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCC(F)(F)CC1)c1cccc(-c2cn[nH]c2)n1
• InChI: InChI=1S/C25H30N6O3.C24H26F2N6O2.C24H29N5O4.C23H25F2N5O3.C23H28N6O3S/c1-25(33)7-9-31(10-8-25)23-15-19(30-11-13-34-14-12-30)5-6-21(23)29-24(32)22-4-2-3-20(28-22)18-16-26-27-17-18;25-24(26)6-8-32(9-7-24)22-14-18(31-10-12-34-13-11-31)4-5-20(22)30-23(33)21-3-1-2-19(29-21)17-15-27-28-16-17;1-24(31)6-8-29(9-7-24)20-14-18(28-10-12-32-13-11-28)2-3-19(20)27-23(30)22-5-4-21(33-22)17-15-25-26-16-17;24-23(25)5-7-30(8-6-23)19-13-17(29-9-11-32-12-10-29)1-2-18(19)28-22(31)21-4-3-20(33-21)16-14-26-27-15-16;1-23(31)4-6-29(7-5-23)20-12-17(28-8-10-32-11-9-28)2-3-18(20)26-21(30)19-15-33-22(27-19)16-13-24-25-14-16/h2-6,15-17,33H,7-14H2,1H3,(H,26,27)(H,29,32);1-5,14-16H,6-13H2,(H,27,28)(H,30,33);2-5,14-16,31H,6-13H2,1H3,(H,25,26)(H,27,30);1-4,13-15H,5-12H2,(H,26,27)(H,28,31);2-3,12-15,31H,4-11H2,1H3,(H,24,25)(H,26,30)
• InChIKey: HIRSBWKCKCGFIS-UHFFFAOYSA-N
• XLogP: 16.79
• TPSA: 493.09 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 34
• Rotatable Bonds: 25
• Heavy Atoms: 167
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2308.65
LogP ≤ 5	16.79
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The IUPAC name of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide (CID 158491025) is N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide.

What is the SMILES notation for N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The canonical SMILES for N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide is CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2ccc(-c3cn[nH]c3)o2)CC1.CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2cccc(-c3cn[nH]c3)n2)CC1.CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2csc(-c3cn[nH]c3)n2)CC1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCC(F)(F)CC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCC(F)(F)CC1)c1cccc(-c2cn[nH]c2)n1.

What is the InChIKey of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The InChIKey is HIRSBWKCKCGFIS-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H30N6O3.C24H26F2N6O2.C24H29N5O4.C23H25F2N5O3.C23H28N6O3S/c1-25(33)7-9-31(10-8-25)23-15-19(30-11-13-34-14-12-30)5-6-21(23)29-24(32)22-4-2-3-20(28-22)18-16-26-27-17-18;25-24(26)6-8-32(9-7-24)22-14-18(31-10-12-34-13-11-31)4-5-20(22)30-23(33)21-3-1-2-19(29-21)17-15-27-28-16-17;1-24(31)6-8-29(9-7-24)20-14-18(28-10-12-32-13-11-28)2-3-19(20)27-23(30)22-5-4-21(33-22)17-15-25-26-16-17;24-23(25)5-7-30(8-6-23)19-13-17(29-9-11-32-12-10-29)1-2-18(19)28-22(31)21-4-3-20(33-21)16-14-26-27-15-16;1-23(31)4-6-29(7-5-23)20-12-17(28-8-10-32-11-9-28)2-3-18(20)26-21(30)19-15-33-22(27-19)16-13-24-25-14-16/h2-6,15-17,33H,7-14H2,1H3,(H,26,27)(H,29,32);1-5,14-16H,6-13H2,(H,27,28)(H,30,33);2-5,14-16,31H,6-13H2,1H3,(H,25,26)(H,27,30);1-4,13-15H,5-12H2,(H,26,27)(H,28,31);2-3,12-15,31H,4-11H2,1H3,(H,24,25)(H,26,30).

What are the key properties of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide has a molecular weight of 2308.65 g/mol, XLogP of 16.79, 25 rotatable bonds, 13 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide is sourced from PubChem (CID 158491025), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).