N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide

C117H137F2N29O15S2 — CID 159933967

About N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide

N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide (PubChem CID 159933967) has the molecular formula C117H137F2N29O15S2 and a molecular weight of 2291.70 g/mol. Its IUPAC name is N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide.

Molecular Properties

• Compound Name: N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide
• PubChem CID: 159933967
• Molecular Formula: C117H137F2N29O15S2
• Molecular Weight: 2291.70 g/mol
• Exact Mass: 2290.03
• IUPAC Name: N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide
• SMILES: CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2ccc(-c3cn[nH]c3)o2)CC1.CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2cccc(-c3cn[nH]c3)n2)CC1.CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2csc(-c3cn[nH]c3)n2)CC1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCC(F)(F)CC1)c1cccc(-c2cn[nH]c2)n1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCOCC1)c1csc(-c2cn[nH]c2)n1
• InChI: InChI=1S/C25H30N6O3.C24H26F2N6O2.C24H29N5O4.C23H28N6O3S.C21H24N6O3S/c1-25(33)7-9-31(10-8-25)23-15-19(30-11-13-34-14-12-30)5-6-21(23)29-24(32)22-4-2-3-20(28-22)18-16-26-27-17-18;25-24(26)6-8-32(9-7-24)22-14-18(31-10-12-34-13-11-31)4-5-20(22)30-23(33)21-3-1-2-19(29-21)17-15-27-28-16-17;1-24(31)6-8-29(9-7-24)20-14-18(28-10-12-32-13-11-28)2-3-19(20)27-23(30)22-5-4-21(33-22)17-15-25-26-16-17;1-23(31)4-6-29(7-5-23)20-12-17(28-8-10-32-11-9-28)2-3-18(20)26-21(30)19-15-33-22(27-19)16-13-24-25-14-16;28-20(18-14-31-21(25-18)15-12-22-23-13-15)24-17-2-1-16(26-3-7-29-8-4-26)11-19(17)27-5-9-30-10-6-27/h2-6,15-17,33H,7-14H2,1H3,(H,26,27)(H,29,32);1-5,14-16H,6-13H2,(H,27,28)(H,30,33);2-5,14-16,31H,6-13H2,1H3,(H,25,26)(H,27,30);2-3,12-15,31H,4-11H2,1H3,(H,24,25)(H,26,30);1-2,11-14H,3-10H2,(H,22,23)(H,24,28)
• InChIKey: NZZPVOKSLXMZCV-UHFFFAOYSA-N
• XLogP: 15.25
• TPSA: 502.07 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 36
• Rotatable Bonds: 25
• Heavy Atoms: 165
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2291.70
LogP ≤ 5	15.25
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The IUPAC name of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide (CID 159933967) is N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide.

What is the SMILES notation for N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The canonical SMILES for N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide is CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2ccc(-c3cn[nH]c3)o2)CC1.CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2cccc(-c3cn[nH]c3)n2)CC1.CC1(O)CCN(c2cc(N3CCOCC3)ccc2NC(=O)c2csc(-c3cn[nH]c3)n2)CC1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCC(F)(F)CC1)c1cccc(-c2cn[nH]c2)n1.O=C(Nc1ccc(N2CCOCC2)cc1N1CCOCC1)c1csc(-c2cn[nH]c2)n1.

What is the InChIKey of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

The InChIKey is NZZPVOKSLXMZCV-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H30N6O3.C24H26F2N6O2.C24H29N5O4.C23H28N6O3S.C21H24N6O3S/c1-25(33)7-9-31(10-8-25)23-15-19(30-11-13-34-14-12-30)5-6-21(23)29-24(32)22-4-2-3-20(28-22)18-16-26-27-17-18;25-24(26)6-8-32(9-7-24)22-14-18(31-10-12-34-13-11-31)4-5-20(22)30-23(33)21-3-1-2-19(29-21)17-15-27-28-16-17;1-24(31)6-8-29(9-7-24)20-14-18(28-10-12-32-13-11-28)2-3-19(20)27-23(30)22-5-4-21(33-22)17-15-25-26-16-17;1-23(31)4-6-29(7-5-23)20-12-17(28-8-10-32-11-9-28)2-3-18(20)26-21(30)19-15-33-22(27-19)16-13-24-25-14-16;28-20(18-14-31-21(25-18)15-12-22-23-13-15)24-17-2-1-16(26-3-7-29-8-4-26)11-19(17)27-5-9-30-10-6-27/h2-6,15-17,33H,7-14H2,1H3,(H,26,27)(H,29,32);1-5,14-16H,6-13H2,(H,27,28)(H,30,33);2-5,14-16,31H,6-13H2,1H3,(H,25,26)(H,27,30);2-3,12-15,31H,4-11H2,1H3,(H,24,25)(H,26,30);1-2,11-14H,3-10H2,(H,22,23)(H,24,28).

What are the key properties of N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide?

N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide has a molecular weight of 2291.70 g/mol, XLogP of 15.25, 25 rotatable bonds, 13 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for N-[2-(4,4-difluoropiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-(2,4-dimorpholin-4-ylphenyl)-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-6-(1H-pyrazol-4-yl)pyridine-2-carboxamide;N-[2-(4-hydroxy-4-methylpiperidin-1-yl)-4-morpholin-4-ylphenyl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide is sourced from PubChem (CID 159933967), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).