(E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide

C185H202F2N42O9 — CID 158446661

About (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide

(E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide (PubChem CID 158446661) has the molecular formula C185H202F2N42O9 and a molecular weight of 3195.93 g/mol. Its IUPAC name is (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide.

Molecular Properties

• Compound Name: (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide
• PubChem CID: 158446661
• Molecular Formula: C185H202F2N42O9
• Molecular Weight: 3195.93 g/mol
• Exact Mass: 3193.66
• IUPAC Name: (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide
• SMILES: CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(C(=O)Nc4ccc(N5CCOCC5)cc4)c23)c1.CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(C(=O)Nc4cccc(F)c4)c23)c1.CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(Nc4ccc(N5CCOCC5)cc4)c23)c1.CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(Nc4cccc(F)c4)c23)c1.CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(Nc4ccccc4)c23)c1
• InChI: InChI=1S/C40H45N9O3.C39H45N9O2.C36H37FN8O2.C35H37FN8O.C35H38N8O/c1-47(2)18-8-13-34(50)26-28-9-6-10-29(25-28)36-35-37(39(51)41-30-14-16-32(17-15-30)49-21-23-52-24-22-49)45-46-38(35)44-40(43-36)42-31-11-7-12-33(27-31)48-19-4-3-5-20-48;1-46(2)18-8-13-34(49)26-28-9-6-10-29(25-28)36-35-37(40-30-14-16-32(17-15-30)48-21-23-50-24-22-48)44-45-38(35)43-39(42-36)41-31-11-7-12-33(27-31)47-19-4-3-5-20-47;1-44(2)17-9-16-30(46)21-24-10-6-11-25(20-24)32-31-33(35(47)38-27-13-7-12-26(37)22-27)42-43-34(31)41-36(40-32)39-28-14-8-15-29(23-28)45-18-4-3-5-19-45;1-43(2)17-9-16-30(45)21-24-10-6-11-25(20-24)32-31-33(37-27-13-7-12-26(36)22-27)41-42-34(31)40-35(39-32)38-28-14-8-15-29(23-28)44-18-4-3-5-19-44;1-42(2)19-11-18-30(44)23-25-12-9-13-26(22-25)32-31-33(36-27-14-5-3-6-15-27)40-41-34(31)39-35(38-32)37-28-16-10-17-29(24-28)43-20-7-4-8-21-43/h6-17,25,27H,3-5,18-24,26H2,1-2H3,(H,41,51)(H2,42,43,44,45,46);6-17,25,27H,3-5,18-24,26H2,1-2H3,(H3,40,41,42,43,44,45);6-16,20,22-23H,3-5,17-19,21H2,1-2H3,(H,38,47)(H2,39,40,41,42,43);6-16,20,22-23H,3-5,17-19,21H2,1-2H3,(H3,37,38,39,40,41,42);3,5-6,9-18,22,24H,4,7-8,19-21,23H2,1-2H3,(H3,36,37,38,39,40,41)/b2*13-8+;2*16-9+;18-11+
• InChIKey: HDLYQBRDNMHNRN-MFUFNTSHSA-N
• XLogP: 32.60
• TPSA: 569.43 Ų
• H-Bond Donors: 15
• H-Bond Acceptors: 44
• Rotatable Bonds: 57
• Heavy Atoms: 238
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3195.93
LogP ≤ 5	32.60
H-Bond Donors ≤ 5	15
H-Bond Acceptors ≤ 10	44

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide?

The IUPAC name of (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide (CID 158446661) is (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide.

What is the SMILES notation for (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide?

The canonical SMILES for (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide is CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(C(=O)Nc4ccc(N5CCOCC5)cc4)c23)c1.CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(C(=O)Nc4cccc(F)c4)c23)c1.CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(Nc4ccc(N5CCOCC5)cc4)c23)c1.CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(Nc4cccc(F)c4)c23)c1.CN(C)C/C=C/C(=O)Cc1cccc(-c2nc(Nc3cccc(N4CCCCC4)c3)nc3n[nH]c(Nc4ccccc4)c23)c1.

What is the InChIKey of (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide?

The InChIKey is HDLYQBRDNMHNRN-MFUFNTSHSA-N. The full InChI is InChI=1S/C40H45N9O3.C39H45N9O2.C36H37FN8O2.C35H37FN8O.C35H38N8O/c1-47(2)18-8-13-34(50)26-28-9-6-10-29(25-28)36-35-37(39(51)41-30-14-16-32(17-15-30)49-21-23-52-24-22-49)45-46-38(35)44-40(43-36)42-31-11-7-12-33(27-31)48-19-4-3-5-20-48;1-46(2)18-8-13-34(49)26-28-9-6-10-29(25-28)36-35-37(40-30-14-16-32(17-15-30)48-21-23-50-24-22-48)44-45-38(35)43-39(42-36)41-31-11-7-12-33(27-31)47-19-4-3-5-20-47;1-44(2)17-9-16-30(46)21-24-10-6-11-25(20-24)32-31-33(35(47)38-27-13-7-12-26(37)22-27)42-43-34(31)41-36(40-32)39-28-14-8-15-29(23-28)45-18-4-3-5-19-45;1-43(2)17-9-16-30(45)21-24-10-6-11-25(20-24)32-31-33(37-27-13-7-12-26(36)22-27)41-42-34(31)40-35(39-32)38-28-14-8-15-29(23-28)44-18-4-3-5-19-44;1-42(2)19-11-18-30(44)23-25-12-9-13-26(22-25)32-31-33(36-27-14-5-3-6-15-27)40-41-34(31)39-35(38-32)37-28-16-10-17-29(24-28)43-20-7-4-8-21-43/h6-17,25,27H,3-5,18-24,26H2,1-2H3,(H,41,51)(H2,42,43,44,45,46);6-17,25,27H,3-5,18-24,26H2,1-2H3,(H3,40,41,42,43,44,45);6-16,20,22-23H,3-5,17-19,21H2,1-2H3,(H,38,47)(H2,39,40,41,42,43);6-16,20,22-23H,3-5,17-19,21H2,1-2H3,(H3,37,38,39,40,41,42);3,5-6,9-18,22,24H,4,7-8,19-21,23H2,1-2H3,(H3,36,37,38,39,40,41)/b2*13-8+;2*16-9+;18-11+.

What are the key properties of (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide?

(E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide has a molecular weight of 3195.93 g/mol, XLogP of 32.60, 57 rotatable bonds, 15 hydrogen bond donors, and 44 hydrogen bond acceptors.

Where does this data come from?

All data for (E)-1-[3-[3-anilino-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]-5-(dimethylamino)pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(3-fluoroanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;(E)-5-(dimethylamino)-1-[3-[3-(4-morpholin-4-ylanilino)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidin-4-yl]phenyl]pent-3-en-2-one;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(3-fluorophenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide;4-[3-[(E)-5-(dimethylamino)-2-oxopent-3-enyl]phenyl]-N-(4-morpholin-4-ylphenyl)-6-(3-piperidin-1-ylanilino)-2H-pyrazolo[3,4-d]pyrimidine-3-carboxamide is sourced from PubChem (CID 158446661), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).