N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide

C139H143F3N38O15 — CID 159533101

About N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide

N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide (PubChem CID 159533101) has the molecular formula C139H143F3N38O15 and a molecular weight of 2642.92 g/mol. Its IUPAC name is N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide.

Molecular Properties

• Compound Name: N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide
• PubChem CID: 159533101
• Molecular Formula: C139H143F3N38O15
• Molecular Weight: 2642.92 g/mol
• Exact Mass: 2641.15
• IUPAC Name: N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide
• SMILES: CC(=O)CNc1nc(NNC(=O)c2ccc(Nc3ccc(-c4cccc(O)c4)cc3)cn2)ncc1F.CC1COCCN1c1nc(NNC(=O)c2ccc(Nc3ccc(-c4cccc(O)c4)cc3)cn2)ncc1F.Cc1cc(N2CCN(CCO)CC2)nc(NNC(=O)c2ccc(Nc3ccc(-c4cccc(O)c4)cc3)cn2)n1.Cc1cc(NCCCN2CCOCC2)nc(NNC(=O)c2ccc(Nc3ccc(-c4cccc(O)c4)cc3)cn2)n1.O=C(NNc1ncc(F)c(N2CCN(CCO)CC2)n1)c1ccc(Nc2ccc(-c3cccc(O)c3)cc2)cn1
• InChI: InChI=1S/C30H34N8O3.C29H32N8O3.C28H29FN8O3.C27H26FN7O3.C25H22FN7O3/c1-21-18-28(31-12-3-13-38-14-16-41-17-15-38)35-30(33-21)37-36-29(40)27-11-10-25(20-32-27)34-24-8-6-22(7-9-24)23-4-2-5-26(39)19-23;1-20-17-27(37-13-11-36(12-14-37)15-16-38)33-29(31-20)35-34-28(40)26-10-9-24(19-30-26)32-23-7-5-21(6-8-23)22-3-2-4-25(39)18-22;29-24-18-31-28(33-26(24)37-12-10-36(11-13-37)14-15-38)35-34-27(40)25-9-8-22(17-30-25)32-21-6-4-19(5-7-21)20-2-1-3-23(39)16-20;1-17-16-38-12-11-35(17)25-23(28)15-30-27(32-25)34-33-26(37)24-10-9-21(14-29-24)31-20-7-5-18(6-8-20)19-3-2-4-22(36)13-19;1-15(34)12-28-23-21(26)14-29-25(31-23)33-32-24(36)22-10-9-19(13-27-22)30-18-7-5-16(6-8-18)17-3-2-4-20(35)11-17/h2,4-11,18-20,34,39H,3,12-17H2,1H3,(H,36,40)(H2,31,33,35,37);2-10,17-19,32,38-39H,11-16H2,1H3,(H,34,40)(H,31,33,35);1-9,16-18,32,38-39H,10-15H2,(H,34,40)(H,31,33,35);2-10,13-15,17,31,36H,11-12,16H2,1H3,(H,33,37)(H,30,32,34);2-11,13-14,30,35H,12H2,1H3,(H,32,36)(H2,28,29,31,33)
• InChIKey: MDGBWNCXQFPVJK-UHFFFAOYSA-N
• XLogP: 18.35
• TPSA: 679.79 Ų
• H-Bond Donors: 24
• H-Bond Acceptors: 48
• Rotatable Bonds: 45
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2642.92
LogP ≤ 5	18.35
H-Bond Donors ≤ 5	24
H-Bond Acceptors ≤ 10	48

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide?

The IUPAC name of N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide (CID 159533101) is N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide.

What is the SMILES notation for N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide?

The canonical SMILES for N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide is CC(=O)CNc1nc(NNC(=O)c2ccc(Nc3ccc(-c4cccc(O)c4)cc3)cn2)ncc1F.CC1COCCN1c1nc(NNC(=O)c2ccc(Nc3ccc(-c4cccc(O)c4)cc3)cn2)ncc1F.Cc1cc(N2CCN(CCO)CC2)nc(NNC(=O)c2ccc(Nc3ccc(-c4cccc(O)c4)cc3)cn2)n1.Cc1cc(NCCCN2CCOCC2)nc(NNC(=O)c2ccc(Nc3ccc(-c4cccc(O)c4)cc3)cn2)n1.O=C(NNc1ncc(F)c(N2CCN(CCO)CC2)n1)c1ccc(Nc2ccc(-c3cccc(O)c3)cc2)cn1.

What is the InChIKey of N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide?

The InChIKey is MDGBWNCXQFPVJK-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H34N8O3.C29H32N8O3.C28H29FN8O3.C27H26FN7O3.C25H22FN7O3/c1-21-18-28(31-12-3-13-38-14-16-41-17-15-38)35-30(33-21)37-36-29(40)27-11-10-25(20-32-27)34-24-8-6-22(7-9-24)23-4-2-5-26(39)19-23;1-20-17-27(37-13-11-36(12-14-37)15-16-38)33-29(31-20)35-34-28(40)26-10-9-24(19-30-26)32-23-7-5-21(6-8-23)22-3-2-4-25(39)18-22;29-24-18-31-28(33-26(24)37-12-10-36(11-13-37)14-15-38)35-34-27(40)25-9-8-22(17-30-25)32-21-6-4-19(5-7-21)20-2-1-3-23(39)16-20;1-17-16-38-12-11-35(17)25-23(28)15-30-27(32-25)34-33-26(37)24-10-9-21(14-29-24)31-20-7-5-18(6-8-20)19-3-2-4-22(36)13-19;1-15(34)12-28-23-21(26)14-29-25(31-23)33-32-24(36)22-10-9-19(13-27-22)30-18-7-5-16(6-8-18)17-3-2-4-20(35)11-17/h2,4-11,18-20,34,39H,3,12-17H2,1H3,(H,36,40)(H2,31,33,35,37);2-10,17-19,32,38-39H,11-16H2,1H3,(H,34,40)(H,31,33,35);1-9,16-18,32,38-39H,10-15H2,(H,34,40)(H,31,33,35);2-10,13-15,17,31,36H,11-12,16H2,1H3,(H,33,37)(H,30,32,34);2-11,13-14,30,35H,12H2,1H3,(H,32,36)(H2,28,29,31,33).

What are the key properties of N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide?

N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide has a molecular weight of 2642.92 g/mol, XLogP of 18.35, 45 rotatable bonds, 24 hydrogen bond donors, and 48 hydrogen bond acceptors.

Where does this data come from?

All data for N'-[5-fluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(3-methylmorpholin-4-yl)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[5-fluoro-4-(2-oxopropylamino)pyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;N'-[4-[4-(2-hydroxyethyl)piperazin-1-yl]-6-methylpyrimidin-2-yl]-5-[4-(3-hydroxyphenyl)anilino]pyridine-2-carbohydrazide;5-[4-(3-hydroxyphenyl)anilino]-N'-[4-methyl-6-(3-morpholin-4-ylpropylamino)pyrimidin-2-yl]pyridine-2-carbohydrazide is sourced from PubChem (CID 159533101), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).