N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide

C114H95BrF5N29O15S4 — CID 159670635

About N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide

N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide (PubChem CID 159670635) has the molecular formula C114H95BrF5N29O15S4 and a molecular weight of 2414.36 g/mol. Its IUPAC name is N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide.

Molecular Properties

• Compound Name: N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide
• PubChem CID: 159670635
• Molecular Formula: C114H95BrF5N29O15S4
• Molecular Weight: 2414.36 g/mol
• Exact Mass: 2411.55
• IUPAC Name: N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide
• SMILES: CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(Br)n(S(=O)(=O)c2ccc(C)cc2)c1.CS(=O)(=O)c1cc([C@H](CC#N)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1.CS(=O)(=O)c1cc([C@H](CO)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1.C[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(NCC(N)=O)nc(S(C)(=O)=O)c1.O=C(NCc1ccnc2[nH]ccc12)c1cncc2c1cnn2-c1ccc(F)cc1
• InChI: InChI=1S/C27H23BrFN5O3S.C23H22FN7O4S.C22H17FN6O3S.C21H15FN6O.C21H18FN5O4S/c1-3-24(18-12-26(28)33(16-18)38(36,37)21-10-4-17(2)5-11-21)32-27(35)23-13-30-15-25-22(23)14-31-34(25)20-8-6-19(29)7-9-20;1-13(14-7-21(27-12-20(25)32)30-22(8-14)36(2,34)35)29-23(33)18-9-26-11-19-17(18)10-28-31(19)16-5-3-15(24)4-6-16;1-33(31,32)21-10-14(7-9-26-21)19(6-8-24)28-22(30)18-11-25-13-20-17(18)12-27-29(20)16-4-2-15(23)3-5-16;22-14-1-3-15(4-2-14)28-19-12-23-10-18(17(19)11-27-28)21(29)26-9-13-5-7-24-20-16(13)6-8-25-20;1-32(30,31)20-8-13(6-7-24-20)18(12-28)26-21(29)17-9-23-11-19-16(17)10-25-27(19)15-4-2-14(22)3-5-15/h4-16,24H,3H2,1-2H3,(H,32,35);3-11,13H,12H2,1-2H3,(H2,25,32)(H,27,30)(H,29,33);2-5,7,9-13,19H,6H2,1H3,(H,28,30);1-8,10-12H,9H2,(H,24,25)(H,26,29);2-11,18,28H,12H2,1H3,(H,26,29)/t24-;13-;19-;;18-/m000.0/s1
• InChIKey: MTYLOBYYEIKDDN-ITFZJBODSA-N
• XLogP: 15.23
• TPSA: 607.03 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 37
• Rotatable Bonds: 31
• Heavy Atoms: 168
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2414.36
LogP ≤ 5	15.23
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	37

Frequently Asked Questions

What is the IUPAC name of N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide?

The IUPAC name of N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide (CID 159670635) is N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide.

What is the SMILES notation for N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide?

The canonical SMILES for N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide is CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(Br)n(S(=O)(=O)c2ccc(C)cc2)c1.CS(=O)(=O)c1cc([C@H](CC#N)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1.CS(=O)(=O)c1cc([C@H](CO)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1.C[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1cc(NCC(N)=O)nc(S(C)(=O)=O)c1.O=C(NCc1ccnc2[nH]ccc12)c1cncc2c1cnn2-c1ccc(F)cc1.

What is the InChIKey of N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide?

The InChIKey is MTYLOBYYEIKDDN-ITFZJBODSA-N. The full InChI is InChI=1S/C27H23BrFN5O3S.C23H22FN7O4S.C22H17FN6O3S.C21H15FN6O.C21H18FN5O4S/c1-3-24(18-12-26(28)33(16-18)38(36,37)21-10-4-17(2)5-11-21)32-27(35)23-13-30-15-25-22(23)14-31-34(25)20-8-6-19(29)7-9-20;1-13(14-7-21(27-12-20(25)32)30-22(8-14)36(2,34)35)29-23(33)18-9-26-11-19-17(18)10-28-31(19)16-5-3-15(24)4-6-16;1-33(31,32)21-10-14(7-9-26-21)19(6-8-24)28-22(30)18-11-25-13-20-17(18)12-27-29(20)16-4-2-15(23)3-5-16;22-14-1-3-15(4-2-14)28-19-12-23-10-18(17(19)11-27-28)21(29)26-9-13-5-7-24-20-16(13)6-8-25-20;1-32(30,31)20-8-13(6-7-24-20)18(12-28)26-21(29)17-9-23-11-19-16(17)10-25-27(19)15-4-2-14(22)3-5-15/h4-16,24H,3H2,1-2H3,(H,32,35);3-11,13H,12H2,1-2H3,(H2,25,32)(H,27,30)(H,29,33);2-5,7,9-13,19H,6H2,1H3,(H,28,30);1-8,10-12H,9H2,(H,24,25)(H,26,29);2-11,18,28H,12H2,1H3,(H,26,29)/t24-;13-;19-;;18-/m000.0/s1.

What are the key properties of N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide?

N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide has a molecular weight of 2414.36 g/mol, XLogP of 15.23, 31 rotatable bonds, 9 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(1S)-1-[2-[(2-amino-2-oxoethyl)amino]-6-methylsulfonyl-4-pyridinyl]ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-1-[5-bromo-1-(4-methylphenyl)sulfonylpyrrol-3-yl]propyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;N-[(1S)-2-cyano-1-(2-methylsulfonyl-4-pyridinyl)ethyl]-1-(4-fluorophenyl)pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-[(1R)-2-hydroxy-1-(2-methylsulfonyl-4-pyridinyl)ethyl]pyrazolo[5,4-c]pyridine-4-carboxamide;1-(4-fluorophenyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)pyrazolo[5,4-c]pyridine-4-carboxamide is sourced from PubChem (CID 159670635), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).