N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide

C109H126F6N20O11 — CID 159983759

About N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide

N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide (PubChem CID 159983759) has the molecular formula C109H126F6N20O11 and a molecular weight of 2006.32 g/mol. Its IUPAC name is N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide.

Molecular Properties

• Compound Name: N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide
• PubChem CID: 159983759
• Molecular Formula: C109H126F6N20O11
• Molecular Weight: 2006.32 g/mol
• Exact Mass: 2004.98
• IUPAC Name: N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide
• SMILES: CC(C)(C)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(OC(F)(F)F)cc1.CC(C)[C@H](C)C(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(F)cc1.Cc1cc(CC(=O)Nc2nc3ccc(C(C)(C)O)nc3n2C2CCC2)ccc1F.Cc1ccc(CC(=O)Nc2nc3ccc(C(C)(C)O)nc3n2C2CCC2)cc1.Cc1ccc(F)cc1CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1C1CCC1
• InChI: InChI=1S/C22H25F3N4O3.2C22H25FN4O2.C22H26N4O2.C21H25FN4O2/c1-20(2,3)12-17(30)28-19-26-15-10-11-16(21(4,5)31)27-18(15)29(19)13-6-8-14(9-7-13)32-22(23,24)25;1-13-11-14(7-8-16(13)23)12-19(28)26-21-24-17-9-10-18(22(2,3)29)25-20(17)27(21)15-5-4-6-15;1-13-7-8-15(23)11-14(13)12-19(28)26-21-24-17-9-10-18(22(2,3)29)25-20(17)27(21)16-5-4-6-16;1-14-7-9-15(10-8-14)13-19(27)25-21-23-17-11-12-18(22(2,3)28)24-20(17)26(21)16-5-4-6-16;1-12(2)13(3)19(27)25-20-23-16-10-11-17(21(4,5)28)24-18(16)26(20)15-8-6-14(22)7-9-15/h6-11,31H,12H2,1-5H3,(H,26,28,30);7-11,15,29H,4-6,12H2,1-3H3,(H,24,26,28);7-11,16,29H,4-6,12H2,1-3H3,(H,24,26,28);7-12,16,28H,4-6,13H2,1-3H3,(H,23,25,27);6-13,28H,1-5H3,(H,23,25,27)/t;;;;13-/m....0/s1
• InChIKey: OGBMGGNRROJOAO-GGVKEFNHSA-N
• XLogP: 20.84
• TPSA: 409.43 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 26
• Rotatable Bonds: 25
• Heavy Atoms: 146
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2006.32
LogP ≤ 5	20.84
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	26

Frequently Asked Questions

What is the IUPAC name of N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

The IUPAC name of N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide (CID 159983759) is N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide.

What is the SMILES notation for N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

The canonical SMILES for N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide is CC(C)(C)CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(OC(F)(F)F)cc1.CC(C)[C@H](C)C(=O)Nc1nc2ccc(C(C)(C)O)nc2n1-c1ccc(F)cc1.Cc1cc(CC(=O)Nc2nc3ccc(C(C)(C)O)nc3n2C2CCC2)ccc1F.Cc1ccc(CC(=O)Nc2nc3ccc(C(C)(C)O)nc3n2C2CCC2)cc1.Cc1ccc(F)cc1CC(=O)Nc1nc2ccc(C(C)(C)O)nc2n1C1CCC1.

What is the InChIKey of N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

The InChIKey is OGBMGGNRROJOAO-GGVKEFNHSA-N. The full InChI is InChI=1S/C22H25F3N4O3.2C22H25FN4O2.C22H26N4O2.C21H25FN4O2/c1-20(2,3)12-17(30)28-19-26-15-10-11-16(21(4,5)31)27-18(15)29(19)13-6-8-14(9-7-13)32-22(23,24)25;1-13-11-14(7-8-16(13)23)12-19(28)26-21-24-17-9-10-18(22(2,3)29)25-20(17)27(21)15-5-4-6-15;1-13-7-8-15(23)11-14(13)12-19(28)26-21-24-17-9-10-18(22(2,3)29)25-20(17)27(21)16-5-4-6-16;1-14-7-9-15(10-8-14)13-19(27)25-21-23-17-11-12-18(22(2,3)28)24-20(17)26(21)16-5-4-6-16;1-12(2)13(3)19(27)25-20-23-16-10-11-17(21(4,5)28)24-18(16)26(20)15-8-6-14(22)7-9-15/h6-11,31H,12H2,1-5H3,(H,26,28,30);7-11,15,29H,4-6,12H2,1-3H3,(H,24,26,28);7-11,16,29H,4-6,12H2,1-3H3,(H,24,26,28);7-12,16,28H,4-6,13H2,1-3H3,(H,23,25,27);6-13,28H,1-5H3,(H,23,25,27)/t;;;;13-/m....0/s1.

What are the key properties of N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide?

N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide has a molecular weight of 2006.32 g/mol, XLogP of 20.84, 25 rotatable bonds, 10 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-fluoro-3-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(5-fluoro-2-methylphenyl)acetamide;N-[3-cyclobutyl-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2-(4-methylphenyl)acetamide;(2S)-N-[3-(4-fluorophenyl)-5-(2-hydroxypropan-2-yl)imidazo[4,5-b]pyridin-2-yl]-2,3-dimethylbutanamide;N-[5-(2-hydroxypropan-2-yl)-3-[4-(trifluoromethoxy)phenyl]imidazo[4,5-b]pyridin-2-yl]-3,3-dimethylbutanamide is sourced from PubChem (CID 159983759), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).