N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide

C126H127F9N30O17S3 — CID 162221678

About N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide

N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide (PubChem CID 162221678) has the molecular formula C126H127F9N30O17S3 and a molecular weight of 2600.78 g/mol. Its IUPAC name is N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide.

Molecular Properties

• Compound Name: N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide
• PubChem CID: 162221678
• Molecular Formula: C126H127F9N30O17S3
• Molecular Weight: 2600.78 g/mol
• Exact Mass: 2598.90
• IUPAC Name: N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide
• SMILES: Cc1cc(-c2ccc(C(=O)Nc3cc4oc(N5CCOCC5)nc4cc3N3CCC(F)(F)CC3)o2)ccn1.Cc1cc(-c2nc(C(=O)Nc3cc4oc(N5CCOCC5)nc4cc3N3CCC(F)(F)CC3)cs2)ccn1.Cc1cc(-c2nc(C(=O)Nc3cc4oc(N5CCOCC5)nc4cc3N3CCC(F)CC3)cs2)ccn1.O=C(Nc1cc2oc(N3CCOCC3)nc2cc1N1CCC(F)(F)CC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1cc2oc(N3CCOCC3)nc2cc1N1CCC(F)(F)CC1)c1csc(-c2cn[nH]c2)n1
• InChI: InChI=1S/C27H27F2N5O4.C26H26F2N6O3S.C26H27FN6O3S.C24H24F2N6O4.C23H23F2N7O3S/c1-17-14-18(4-7-30-17)22-2-3-23(37-22)25(35)31-19-16-24-20(32-26(38-24)34-10-12-36-13-11-34)15-21(19)33-8-5-27(28,29)6-9-33;1-16-12-17(2-5-29-16)24-31-20(15-38-24)23(35)30-18-14-22-19(32-25(37-22)34-8-10-36-11-9-34)13-21(18)33-6-3-26(27,28)4-7-33;1-16-12-17(2-5-28-16)25-30-21(15-37-25)24(34)29-19-14-23-20(13-22(19)32-6-3-18(27)4-7-32)31-26(36-23)33-8-10-35-11-9-33;25-24(26)3-5-31(6-4-24)18-11-17-21(36-23(30-17)32-7-9-34-10-8-32)12-16(18)29-22(33)20-2-1-19(35-20)15-13-27-28-14-15;24-23(25)1-3-31(4-2-23)18-9-16-19(35-22(30-16)32-5-7-34-8-6-32)10-15(18)28-20(33)17-13-36-21(29-17)14-11-26-27-12-14/h2-4,7,14-16H,5-6,8-13H2,1H3,(H,31,35);2,5,12-15H,3-4,6-11H2,1H3,(H,30,35);2,5,12-15,18H,3-4,6-11H2,1H3,(H,29,34);1-2,11-14H,3-10H2,(H,27,28)(H,29,33);9-13H,1-8H2,(H,26,27)(H,28,33)
• InChIKey: ZUFBFCROTMQUOS-UHFFFAOYSA-N
• XLogP: 22.91
• TPSA: 515.18 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 43
• Rotatable Bonds: 25
• Heavy Atoms: 185
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2600.78
LogP ≤ 5	22.91
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	43

Frequently Asked Questions

What is the IUPAC name of N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide?

The IUPAC name of N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide (CID 162221678) is N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide.

What is the SMILES notation for N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide?

The canonical SMILES for N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide is Cc1cc(-c2ccc(C(=O)Nc3cc4oc(N5CCOCC5)nc4cc3N3CCC(F)(F)CC3)o2)ccn1.Cc1cc(-c2nc(C(=O)Nc3cc4oc(N5CCOCC5)nc4cc3N3CCC(F)(F)CC3)cs2)ccn1.Cc1cc(-c2nc(C(=O)Nc3cc4oc(N5CCOCC5)nc4cc3N3CCC(F)CC3)cs2)ccn1.O=C(Nc1cc2oc(N3CCOCC3)nc2cc1N1CCC(F)(F)CC1)c1ccc(-c2cn[nH]c2)o1.O=C(Nc1cc2oc(N3CCOCC3)nc2cc1N1CCC(F)(F)CC1)c1csc(-c2cn[nH]c2)n1.

What is the InChIKey of N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide?

The InChIKey is ZUFBFCROTMQUOS-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H27F2N5O4.C26H26F2N6O3S.C26H27FN6O3S.C24H24F2N6O4.C23H23F2N7O3S/c1-17-14-18(4-7-30-17)22-2-3-23(37-22)25(35)31-19-16-24-20(32-26(38-24)34-10-12-36-13-11-34)15-21(19)33-8-5-27(28,29)6-9-33;1-16-12-17(2-5-29-16)24-31-20(15-38-24)23(35)30-18-14-22-19(32-25(37-22)34-8-10-36-11-9-34)13-21(18)33-6-3-26(27,28)4-7-33;1-16-12-17(2-5-28-16)25-30-21(15-37-25)24(34)29-19-14-23-20(13-22(19)32-6-3-18(27)4-7-32)31-26(36-23)33-8-10-35-11-9-33;25-24(26)3-5-31(6-4-24)18-11-17-21(36-23(30-17)32-7-9-34-10-8-32)12-16(18)29-22(33)20-2-1-19(35-20)15-13-27-28-14-15;24-23(25)1-3-31(4-2-23)18-9-16-19(35-22(30-16)32-5-7-34-8-6-32)10-15(18)28-20(33)17-13-36-21(29-17)14-11-26-27-12-14/h2-4,7,14-16H,5-6,8-13H2,1H3,(H,31,35);2,5,12-15H,3-4,6-11H2,1H3,(H,30,35);2,5,12-15,18H,3-4,6-11H2,1H3,(H,29,34);1-2,11-14H,3-10H2,(H,27,28)(H,29,33);9-13H,1-8H2,(H,26,27)(H,28,33).

What are the key properties of N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide?

N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide has a molecular weight of 2600.78 g/mol, XLogP of 22.91, 25 rotatable bonds, 7 hydrogen bond donors, and 43 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(2-methyl-4-pyridinyl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-5-(1H-pyrazol-4-yl)furan-2-carboxamide;N-[5-(4,4-difluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(1H-pyrazol-4-yl)-1,3-thiazole-4-carboxamide;N-[5-(4-fluoropiperidin-1-yl)-2-morpholin-4-yl-1,3-benzoxazol-6-yl]-2-(2-methyl-4-pyridinyl)-1,3-thiazole-4-carboxamide is sourced from PubChem (CID 162221678), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).