8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine

C14H15F2N3 — CID 170328485

IUPAC8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine
SMILESNc1cc(N2CCC(F)(F)CC2)c2ncccc2c1
InChIInChI=1S/C14H15F2N3/c15-14(16)3-6-19(7-4-14)12-9-11(17)8-10-2-1-5-18-13(10)12/h1-2,5,8-9H,3-4,6-7,17H2
InChIKeyYKNNQUUFEJIOSW-UHFFFAOYSA-N
MW263.29 g/mol
LogP3.05
Rot. Bonds1

About 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine

8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine (PubChem CID 170328485) has the molecular formula C14H15F2N3 and a molecular weight of 263.29 g/mol. Its IUPAC name is 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine.

Molecular Properties

Compound Name8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine
PubChem CID170328485
Molecular FormulaC14H15F2N3
Molecular Weight263.29 g/mol
Exact Mass263.12
IUPAC Name8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine
SMILESNc1cc(N2CCC(F)(F)CC2)c2ncccc2c1
InChIInChI=1S/C14H15F2N3/c15-14(16)3-6-19(7-4-14)12-9-11(17)8-10-2-1-5-18-13(10)12/h1-2,5,8-9H,3-4,6-7,17H2
InChIKeyYKNNQUUFEJIOSW-UHFFFAOYSA-N
XLogP3.05
TPSA42.15 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds1
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500263.29
LogP ≤ 53.05
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'aniline', 'substructure': 'N/A'}

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Related Compounds

8-(4,4-difluoropiperidin-1-yl)quinoline-6-carbaldehyde
CID 170328398
6-[(1Z,3Z,5E)-2,4-difluoro-6-nitroocta-1,3,5,7-tetraenyl]-8-(4,4-difluoropiperidin-1-yl)quinoline
CID 177282887
8-chloroquinolin-6-amine
CID 53435994
[2-(4,4-difluoropiperidin-1-yl)-3-pyridinyl]methanamine
CID 68582946
8-piperazin-1-yl-6-propan-2-yloxyquinoline
CID 141025373
2-[[3-(6-azaspiro[2.5]octan-6-yl)-4-[[8-(4,4-difluoropiperidin-1-yl)quinolin-6-yl]carbamoyl]phenyl]sulfamoyl]ethyl (2R)-2-amino-3-methylbutanoate
CID 176791850
3-bromo-2-(3,3-difluoropyrrolidin-1-yl)pyridine
CID 86810762
1-quinolin-8-ylpiperidin-4-amine
CID 81224219
3-(4,4-difluoropiperidin-1-yl)quinoline
CID 144553377
8-(4-methylpiperazin-1-yl)quinoline
CID 20701166
1-(4,4-difluoropiperidin-1-yl)-2,7-naphthyridin-3-amine
CID 170331623
4,4-difluoro-1-(2-propan-2-ylphenyl)piperidine
CID 117007764

Frequently Asked Questions

What is the IUPAC name of 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine?
The IUPAC name of 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine (CID 170328485) is 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine.
What is the SMILES notation for 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine?
The canonical SMILES for 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine is Nc1cc(N2CCC(F)(F)CC2)c2ncccc2c1.
What is the InChIKey of 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine?
The InChIKey is YKNNQUUFEJIOSW-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H15F2N3/c15-14(16)3-6-19(7-4-14)12-9-11(17)8-10-2-1-5-18-13(10)12/h1-2,5,8-9H,3-4,6-7,17H2.
What are the key properties of 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine?
8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine has a molecular weight of 263.29 g/mol, XLogP of 3.05, 1 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 8-(4,4-difluoropiperidin-1-yl)quinolin-6-amine is sourced from PubChem (CID 170328485), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).