2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide

C21H17FN4O3S — CID 18279498

IUPAC2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide
SMILESCC1(c2ccc(F)cc2)NC(=O)N(CC(=O)Nc2ccc(-c3nccs3)cc2)C1=O
InChIInChI=1S/C21H17FN4O3S/c1-21(14-4-6-15(22)7-5-14)19(28)26(20(29)25-21)12-17(27)24-16-8-2-13(3-9-16)18-23-10-11-30-18/h2-11H,12H2,1H3,(H,24,27)(H,25,29)
InChIKeyFXNNHGXTOOZREQ-UHFFFAOYSA-N
MW424.46 g/mol
LogP3.35
Rot. Bonds5

About 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide

2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide (PubChem CID 18279498) has the molecular formula C21H17FN4O3S and a molecular weight of 424.46 g/mol. Its IUPAC name is 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide.

Molecular Properties

Compound Name2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide
PubChem CID18279498
Molecular FormulaC21H17FN4O3S
Molecular Weight424.46 g/mol
Exact Mass424.10
IUPAC Name2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide
SMILESCC1(c2ccc(F)cc2)NC(=O)N(CC(=O)Nc2ccc(-c3nccs3)cc2)C1=O
InChIInChI=1S/C21H17FN4O3S/c1-21(14-4-6-15(22)7-5-14)19(28)26(20(29)25-21)12-17(27)24-16-8-2-13(3-9-16)18-23-10-11-30-18/h2-11H,12H2,1H3,(H,24,27)(H,25,29)
InChIKeyFXNNHGXTOOZREQ-UHFFFAOYSA-N
XLogP3.35
TPSA91.40 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds5
Heavy Atoms30
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500424.46
LogP ≤ 53.35
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'hydantoin', 'substructure': 'N/A'}

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Related Compounds

N-(4-fluorophenyl)-2-[(4S)-4-methyl-4-(4-methylphenyl)-2,5-dioxoimidazolidin-1-yl]acetamide
CID 2581954
2-(4-ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide
CID 16549239
2-[(4R)-4-(4-tert-butylphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(4-fluorophenyl)acetamide
CID 2084864
2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(trifluoromethyl)phenyl]acetamide
CID 46671942
N-[4-[[2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetyl]amino]phenyl]-2-methylpropanamide
CID 46513573
2-[4-(3,4-dichlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(4-fluorophenyl)acetamide
CID 55434764
N-[4-(2-amino-2-oxoethoxy)phenyl]-2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide
CID 55567225
2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(4-fluorophenyl)acetamide
CID 5031590
2-[(4S)-2',5'-dioxospiro[2,3-dihydro-1H-naphthalene-4,4'-imidazolidine]-1'-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide
CID 41080271
N-(3-fluoro-4-methylphenyl)-2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]acetamide
CID 51250072
2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(4-piperidin-1-ylphenyl)acetamide
CID 42918889
2-[(4R)-4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide
CID 30550988

Frequently Asked Questions

What is the IUPAC name of 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide?
The IUPAC name of 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide (CID 18279498) is 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide.
What is the SMILES notation for 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide?
The canonical SMILES for 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide is CC1(c2ccc(F)cc2)NC(=O)N(CC(=O)Nc2ccc(-c3nccs3)cc2)C1=O.
What is the InChIKey of 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide?
The InChIKey is FXNNHGXTOOZREQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H17FN4O3S/c1-21(14-4-6-15(22)7-5-14)19(28)26(20(29)25-21)12-17(27)24-16-8-2-13(3-9-16)18-23-10-11-30-18/h2-11H,12H2,1H3,(H,24,27)(H,25,29).
What are the key properties of 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide?
2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide has a molecular weight of 424.46 g/mol, XLogP of 3.35, 5 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[4-(1,3-thiazol-2-yl)phenyl]acetamide is sourced from PubChem (CID 18279498), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).