5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide

C21H23FN4O2 — CID 46927260

IUPAC5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide
SMILESCNC(=O)c1ccnc(NC(=O)N2CCC3(CC2)Cc2ccc(F)cc2C3)c1
InChIInChI=1S/C21H23FN4O2/c1-23-19(27)14-4-7-24-18(11-14)25-20(28)26-8-5-21(6-9-26)12-15-2-3-17(22)10-16(15)13-21/h2-4,7,10-11H,5-6,8-9,12-13H2,1H3,(H,23,27)(H,24,25,28)
InChIKeyPHYZSAULJWQSEQ-UHFFFAOYSA-N
MW382.44 g/mol
LogP2.99
Rot. Bonds2

About 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide

5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide (PubChem CID 46927260) has the molecular formula C21H23FN4O2 and a molecular weight of 382.44 g/mol. Its IUPAC name is 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide.

Molecular Properties

Compound Name5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide
PubChem CID46927260
Molecular FormulaC21H23FN4O2
Molecular Weight382.44 g/mol
Exact Mass382.18
IUPAC Name5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide
SMILESCNC(=O)c1ccnc(NC(=O)N2CCC3(CC2)Cc2ccc(F)cc2C3)c1
InChIInChI=1S/C21H23FN4O2/c1-23-19(27)14-4-7-24-18(11-14)25-20(28)26-8-5-21(6-9-26)12-15-2-3-17(22)10-16(15)13-21/h2-4,7,10-11H,5-6,8-9,12-13H2,1H3,(H,23,27)(H,24,25,28)
InChIKeyPHYZSAULJWQSEQ-UHFFFAOYSA-N
XLogP2.99
TPSA74.33 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500382.44
LogP ≤ 52.99
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

Analyze 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide with MolForge

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Related Compounds

2-[(6-fluorospiro[3,4-dihydrochromene-2,4'-piperidine]-1'-carbonyl)amino]pyridine-4-carboxylic acid
CID 67122772
8-chloro-N-[4-(methylcarbamoyl)-2-pyridinyl]-4-oxospiro[3H-chromene-2,4'-piperidine]-1'-carboxamide
CID 46927020
6-fluoro-N-[4-[(1-methylpyrazol-4-yl)methylcarbamoyl]-2-pyridinyl]spiro[3,4-dihydrochromene-2,4'-piperidine]-1'-carboxamide
CID 46927098
3-azaspiro[5.5]undecan-3-yl-[2-(methylamino)-4-pyridinyl]methanone
CID 62930860
N-(5-fluoro-2-pyridinyl)-2-(methylamino)pyridine-4-carboxamide
CID 65479896
N-[4-[4-[(4-fluorophenoxy)methyl]-4-hydroxyazepane-1-carbonyl]-2-pyridinyl]acetamide
CID 155991080
5-fluoro-N-methyl-1,3-dihydroisoindole-2-carboxamide
CID 175773475
N-(2,4-difluorophenyl)-4-methyl-4-(methylamino)piperidine-1-carboxamide
CID 115304661
2-(cyclopropylamino)-N-methylpyridine-4-carboxamide
CID 130666257
N-(4-methyl-2-pyridinyl)azepane-1-carboxamide
CID 127514123
N-(2-bromo-4-fluorophenyl)-2-(methylamino)pyridine-4-carboxamide
CID 62165424
N-[(2-amino-4-fluorophenyl)methyl]-6-fluoro-4-oxospiro[1,3-dihydronaphthalene-2,4'-piperidine]-1'-carboxamide
CID 167709873

Frequently Asked Questions

What is the IUPAC name of 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide?
The IUPAC name of 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide (CID 46927260) is 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide.
What is the SMILES notation for 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide?
The canonical SMILES for 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide is CNC(=O)c1ccnc(NC(=O)N2CCC3(CC2)Cc2ccc(F)cc2C3)c1.
What is the InChIKey of 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide?
The InChIKey is PHYZSAULJWQSEQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H23FN4O2/c1-23-19(27)14-4-7-24-18(11-14)25-20(28)26-8-5-21(6-9-26)12-15-2-3-17(22)10-16(15)13-21/h2-4,7,10-11H,5-6,8-9,12-13H2,1H3,(H,23,27)(H,24,25,28).
What are the key properties of 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide?
5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide has a molecular weight of 382.44 g/mol, XLogP of 2.99, 2 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 5-fluoro-N-[4-(methylcarbamoyl)-2-pyridinyl]spiro[1,3-dihydroindene-2,4'-piperidine]-1'-carboxamide is sourced from PubChem (CID 46927260), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).