About Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate
Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate (PubChem CID 59322280) has the molecular formula C18H21F3N4O3
and a molecular weight of 398.40 g/mol. Its IUPAC name is tert-butyl 4-cyano-4-[[6-(trifluoromethyl)-3-pyridinyl]carbamoyl]piperidine-1-carboxylate.
Molecular Properties
| Compound Name | Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate |
| PubChem CID | 59322280 |
| Molecular Formula | C18H21F3N4O3 |
| Molecular Weight | 398.40 g/mol |
| Exact Mass | 398.16 |
| IUPAC Name | tert-butyl 4-cyano-4-[[6-(trifluoromethyl)-3-pyridinyl]carbamoyl]piperidine-1-carboxylate |
| SMILES | CC(C)(C)OC(=O)N1CCC(CC1)(C#N)C(=O)NC2=CN=C(C=C2)C(F)(F)F |
| InChI | InChI=1S/C18H21F3N4O3/c1-16(2,3)28-15(27)25-8-6-17(11-22,7-9-25)14(26)24-12-4-5-13(23-10-12)18(19,20)21/h4-5,10H,6-9H2,1-3H3,(H,24,26) |
| InChIKey | JKJKNFUXDUGHTM-UHFFFAOYSA-N |
| XLogP | 2.60 |
| TPSA | 95.30 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 28 |
| Complexity | 643 |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 398.40 |
| LogP ≤ 5 | 2.60 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 8 |
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Frequently Asked Questions
What is the IUPAC name of Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate?
The IUPAC name of Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate (CID 59322280) is tert-butyl 4-cyano-4-[[6-(trifluoromethyl)-3-pyridinyl]carbamoyl]piperidine-1-carboxylate.
What is the SMILES notation for Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate?
The canonical SMILES for Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate is CC(C)(C)OC(=O)N1CCC(CC1)(C#N)C(=O)NC2=CN=C(C=C2)C(F)(F)F.
What is the InChIKey of Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate?
The InChIKey is JKJKNFUXDUGHTM-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H21F3N4O3/c1-16(2,3)28-15(27)25-8-6-17(11-22,7-9-25)14(26)24-12-4-5-13(23-10-12)18(19,20)21/h4-5,10H,6-9H2,1-3H3,(H,24,26).
What are the key properties of Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate?
Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate has a molecular weight of 398.40 g/mol, XLogP of 2.60, 4 rotatable bonds, 1 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for Tert-butyl 4-cyano-4-(6-(trifluoromethyl)-pyridin-3-ylcarbamoyl)piperidine-1-carboxylate is sourced from PubChem (CID 59322280), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).