(5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione

C27H28N6O5 — CID 88570089

About (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione

(5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione (PubChem CID 88570089) has the molecular formula C27H28N6O5 and a molecular weight of 516.56 g/mol. Its IUPAC name is (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione.

Molecular Properties

• Compound Name: (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione
• PubChem CID: 88570089
• Molecular Formula: C27H28N6O5
• Molecular Weight: 516.56 g/mol
• Exact Mass: 516.21
• IUPAC Name: (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione
• SMILES: COc1ccc2c(c1)C(=O)N(C[C@@]1(C#Cc3ccc(/C(=N\O)N4CCNC[C@@H]4C)cc3)NC(=O)NC1=O)C2
• InChI: InChI=1S/C27H28N6O5/c1-17-14-28-11-12-33(17)23(31-37)19-5-3-18(4-6-19)9-10-27(25(35)29-26(36)30-27)16-32-15-20-7-8-21(38-2)13-22(20)24(32)34/h3-8,13,17,28,37H,11-12,14-16H2,1-2H3,(H2,29,30,35,36)/b31-23+/t17-,27+/m0/s1
• InChIKey: ITEYVAAVSASSKJ-VRNUXYGZSA-N
• XLogP: 0.71
• TPSA: 135.60 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 7
• Rotatable Bonds: 4
• Heavy Atoms: 38
• Complexity: —

Lipinski Rule of Five

1 violation

Rule	Value
MW ≤ 500	516.56
LogP ≤ 5	0.71
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	7

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}, {'alert_name': 'imine_1', 'substructure': 'N/A'}, {'alert_name': 'imine_2', 'substructure': 'N/A'}, {'alert_name': 'oxime_1', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione?

The IUPAC name of (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione (CID 88570089) is (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione.

What is the SMILES notation for (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione?

The canonical SMILES for (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione is COc1ccc2c(c1)C(=O)N(C[C@@]1(C#Cc3ccc(/C(=N\O)N4CCNC[C@@H]4C)cc3)NC(=O)NC1=O)C2.

What is the InChIKey of (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione?

The InChIKey is ITEYVAAVSASSKJ-VRNUXYGZSA-N. The full InChI is InChI=1S/C27H28N6O5/c1-17-14-28-11-12-33(17)23(31-37)19-5-3-18(4-6-19)9-10-27(25(35)29-26(36)30-27)16-32-15-20-7-8-21(38-2)13-22(20)24(32)34/h3-8,13,17,28,37H,11-12,14-16H2,1-2H3,(H2,29,30,35,36)/b31-23+/t17-,27+/m0/s1.

What are the key properties of (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione?

(5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione has a molecular weight of 516.56 g/mol, XLogP of 0.71, 4 rotatable bonds, 4 hydrogen bond donors, and 7 hydrogen bond acceptors.

Where does this data come from?

All data for (5R)-5-[2-[4-[(E)-N-hydroxy-C-[(2S)-2-methylpiperazin-1-yl]carbonimidoyl]phenyl]ethynyl]-5-[(5-methoxy-3-oxo-1H-isoindol-2-yl)methyl]imidazolidine-2,4-dione is sourced from PubChem (CID 88570089), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).