[(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine

C6H11F3N2 — CID 95396558

IUPAC[(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine
SMILESNC[C@H]1CC[C@H](C(F)(F)F)N1
InChIInChI=1S/C6H11F3N2/c7-6(8,9)5-2-1-4(3-10)11-5/h4-5,11H,1-3,10H2/t4-,5-/m1/s1
InChIKeyZZYQFRTWAYDKCV-RFZPGFLSSA-N
MW168.16 g/mol
LogP0.63
Rot. Bonds1

About [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine

[(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine (PubChem CID 95396558) has the molecular formula C6H11F3N2 and a molecular weight of 168.16 g/mol. Its IUPAC name is [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine.

Molecular Properties

Compound Name[(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine
PubChem CID95396558
Molecular FormulaC6H11F3N2
Molecular Weight168.16 g/mol
Exact Mass168.09
IUPAC Name[(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine
SMILESNC[C@H]1CC[C@H](C(F)(F)F)N1
InChIInChI=1S/C6H11F3N2/c7-6(8,9)5-2-1-4(3-10)11-5/h4-5,11H,1-3,10H2/t4-,5-/m1/s1
InChIKeyZZYQFRTWAYDKCV-RFZPGFLSSA-N
XLogP0.63
TPSA38.05 Ų
H-Bond Donors2
H-Bond Acceptors2
Rotatable Bonds1
Heavy Atoms11
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500168.16
LogP ≤ 50.63
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 102

Analyze [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

3-[(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]propanoic acid
CID 125424409
(2R,6R)-2,6-bis(trifluoromethyl)piperidine
CID 96551753
2-(trifluoromethyl)-6-(3,3,3-trifluoropropyl)piperidine
CID 106779737
2-(2-methylpropyl)-6-(trifluoromethyl)piperidine;hydrochloride
CID 119031618
2-(3,3-dimethylbutyl)-6-(trifluoromethyl)piperidine
CID 106778866
3-amino-6-(trifluoromethyl)piperidin-2-one
CID 43810944
(2R,6R)-2-methyl-6-(trifluoromethyl)piperidine
CID 95366768
2-(2-ethylhexyl)-6-(trifluoromethyl)piperidine
CID 106777958
2-[(2-ethyl-1,2,4-triazol-3-yl)methyl]-6-(trifluoromethyl)piperidine
CID 106780142
2-(trifluoromethyl)azetidine;hydrochloride
CID 119031729
(6-methyldiazinan-3-yl)methanamine
CID 91262068
2-cycloheptyl-6-(trifluoromethyl)piperidine
CID 106781025

Frequently Asked Questions

What is the IUPAC name of [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine?
The IUPAC name of [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine (CID 95396558) is [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine.
What is the SMILES notation for [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine?
The canonical SMILES for [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine is NC[C@H]1CC[C@H](C(F)(F)F)N1.
What is the InChIKey of [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine?
The InChIKey is ZZYQFRTWAYDKCV-RFZPGFLSSA-N. The full InChI is InChI=1S/C6H11F3N2/c7-6(8,9)5-2-1-4(3-10)11-5/h4-5,11H,1-3,10H2/t4-,5-/m1/s1.
What are the key properties of [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine?
[(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine has a molecular weight of 168.16 g/mol, XLogP of 0.63, 1 rotatable bonds, 2 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for [(2R,5R)-5-(trifluoromethyl)pyrrolidin-2-yl]methanamine is sourced from PubChem (CID 95396558), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).