Arbutamine

CARDIOVASCULAR SYSTEM

Key facts

Arbutamine is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1997. DrugCentral lists 1 molecular target, including ADRB1. Recorded indications include Cardiac Function Studies.

• Approval status: ofm (first approved 1997 by the FDA).
• Molecular targets: ADRB1 (1 listed in DrugCentral).
• Indications: Cardiac Function Studies.
• ATC code: C01CA22 (Adrenergic and dopaminergic agents).
• Molecular formula: C18H23NO4; molecular weight 317.38 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Cardiac Function Studies

Contraindications (9)

• Acute coronary syndrome
• Angle-closure glaucoma
• Cardiac pacemaker, device
• Chronic heart failure
• Hypertensive urgency
• Hyperthyroidism
• Idiopathic hypertrophic subaortic stenosis
• Supraventricular arrhythmia
• Tachyarrhythmia

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Beta-1 adrenergic receptor	ADRB1	agonist	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1997-09-12	FDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
C01CA22	CARDIOVASCULAR SYSTEM › CARDIAC THERAPY › CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES › Adrenergic and dopaminergic agents

Chemical structure

• Molecular formula: C₁₈H₂₃NO₄
• Molecular weight: 317.38 g/mol
• CAS number: 128470-16-6
• InChIKey: IIRWWTKISYTTBL-SFHVURJKSA-N
• PubChem CID: 60789

O[C@@H](CNCCCCC1=CC=C(O)C=C1)C1=CC(O)=C(O)C=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Arbutamine used for?

DrugCentral lists the following indications for Arbutamine: Cardiac Function Studies.

How does Arbutamine work?

Its molecular targets in DrugCentral include ADRB1 (agonist).

When was Arbutamine first approved?

Arbutamine was first approved by the FDA in 1997.

What is the chemical formula of Arbutamine?

Arbutamine has the molecular formula C18H23NO4 and a molecular weight of 317.38 g/mol.

Sources

• DrugCentral drug card 237 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200385 — compound record and bioactivity
• PubChem CID 60789 — chemical identifiers
• DrugBank DB01102 — drug record
• FDA UNII B07L15YAEV — substance identity
• DailyMed: FDA labels for Arbutamine — current prescribing information (label search)
• UniProt P08588 (ADRB1) — target protein

How this page is built: methodology · editorial policy & corrections.