Etilefrine

CARDIOVASCULAR SYSTEM

Key facts

Etilefrine is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1929. DrugCentral lists 1 molecular target, including ADRB1.

• Molecular targets: ADRB1 (1 listed in DrugCentral).
• ATC code: C01CA01 (Adrenergic and dopaminergic agents).
• Molecular formula: C10H15NO2; molecular weight 181.24 g/mol.

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Beta-1 adrenergic receptor	ADRB1	agonist	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1929-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
C01CA01	CARDIOVASCULAR SYSTEM › CARDIAC THERAPY › CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES › Adrenergic and dopaminergic agents
C01CA51	CARDIOVASCULAR SYSTEM › CARDIAC THERAPY › CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES › Adrenergic and dopaminergic agents

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Cafe au lait spots	50.9
Sulphaemoglobinaemia	50.5
Anal stenosis	49.8
Wolff-Parkinson-White syndrome	45.9
Kidney duplex	45.7
Ear malformation	44.4
Pulmonary valve stenosis	42.6
Motor developmental delay	42.6
Phimosis	42.4
Postoperative adhesion	42.3
Dacryostenosis acquired	42.2
Sepsis neonatal	41.5

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Etilefrine is on its molecule page.

• Molecular formula: C₁₀H₁₅NO₂
• Molecular weight: 181.24 g/mol
• CAS number: 709-55-7
• InChIKey: SQVIAVUSQAWMKL-UHFFFAOYSA-N
• PubChem CID: 3306

CCNCC(O)C1=CC(O)=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Etilefrine work?

Its molecular targets in DrugCentral include ADRB1 (agonist).

When was Etilefrine first approved?

Etilefrine was first approved by the YEAR INTRODUCED in 1929.

What is the chemical formula of Etilefrine?

Etilefrine has the molecular formula C10H15NO2 and a molecular weight of 181.24 g/mol.

Sources

• DrugCentral drug card 1101 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL86882 — compound record and bioactivity
• PubChem CID 3306 — chemical identifiers
• DrugBank DB08985 — drug record
• FDA UNII ZB6F8MY53V — substance identity
• UniProt P08588 (ADRB1) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.