Bambuterol

RESPIRATORY SYSTEM

Key facts

Bambuterol is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1990. DrugCentral lists 7 molecular targets, including Bche, BCHE and BCHE.

• Molecular targets: Bche, BCHE, BCHE and CYP2D6 (7 listed in DrugCentral).
• ATC code: R03CC12 (Selective beta-2-adrenoreceptor agonists).
• Molecular formula: C18H29N3O5; molecular weight 367.45 g/mol.

Mechanism & targets

Molecular targets (7)

Target	Gene	Action	Activity
Butyrylcholinesterase; Protein Bche	Bche	unknown	IC50 8.52
Cholinesterase	BCHE	inhibitor	IC50 8.50
Cholinesterase	BCHE	unknown	IC50 6.92
Cytochrome P450 2D6	CYP2D6	unknown	IC50 5.70
Acetylcholinesterase	Ache	unknown	IC50 4.52
Acetylcholinesterase	ACHE	unknown	Ki 3.25
Beta-2 adrenergic receptor	ADRB2	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1990-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
R03CC12	RESPIRATORY SYSTEM › DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES › ADRENERGICS FOR SYSTEMIC USE › Selective beta-2-adrenoreceptor agonists

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Acute kidney injury	82.0

Chemical structure

• Molecular formula: C₁₈H₂₉N₃O₅
• Molecular weight: 367.45 g/mol
• CAS number: 81732-65-2
• InChIKey: ANZXOIAKUNOVQU-UHFFFAOYSA-N
• PubChem CID: 54766

CN(C)C(=O)OC1=CC(=CC(OC(=O)N(C)C)=C1)C(O)CNC(C)(C)C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Bambuterol work?

Its molecular targets in DrugCentral include Bche, BCHE (inhibitor), BCHE and CYP2D6.

When was Bambuterol first approved?

Bambuterol was first approved by the YEAR INTRODUCED in 1990.

What is the chemical formula of Bambuterol?

Bambuterol has the molecular formula C18H29N3O5 and a molecular weight of 367.45 g/mol.

Sources

• DrugCentral drug card 285 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL521589 — compound record and bioactivity
• PubChem CID 54766 — chemical identifiers
• DrugBank DB01408 — drug record
• FDA UNII Y1850G1OVC — substance identity
• UniProt P06276 (BCHE) — target protein
• UniProt P10635 (CYP2D6) — target protein
• UniProt P22303 (ACHE) — target protein
• UniProt P07550 (ADRB2) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.