Bilastine

RESPIRATORY SYSTEM

Key facts

Bilastine is a drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including HRH1. Recorded indications include Allergic rhinitis and Urticaria.

• Molecular targets: HRH1 (1 listed in DrugCentral).
• Indications: Allergic rhinitis and Urticaria.
• ATC code: R06AX29 (Other antihistamines for systemic use).
• Molecular formula: C28H37N3O3; molecular weight 463.62 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (2)

• Allergic rhinitis
• Urticaria

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Histamine H1 receptor	HRH1	antagonist	Ki 7.19

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	PMDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
R06AX29	RESPIRATORY SYSTEM › ANTIHISTAMINES FOR SYSTEMIC USE › ANTIHISTAMINES FOR SYSTEMIC USE › Other antihistamines for systemic use
S01GX13	SENSORY ORGANS › OPHTHALMOLOGICALS › DECONGESTANTS AND ANTIALLERGICS › Other antiallergics

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Urticaria	692.8
Pruritus	302.3
Angioedema	278.1
Chronic spontaneous urticaria	182.7
Erythema	123.2
Urticaria chronic	116.8
Skin plaque	111.0
Inappropriate schedule of product administration	106.2
Anaphylactic reaction	94.3
Urticarial vasculitis	90.0
Death	85.5
Asthma	75.8

Chemical structure

• Molecular formula: C₂₈H₃₇N₃O₃
• Molecular weight: 463.62 g/mol
• CAS number: —
• InChIKey: ACCMWZWAEFYUGZ-UHFFFAOYSA-N
• PubChem CID: 185460

CCOCCN1C(=NC2=C1C=CC=C2)C1CCN(CCC2=CC=C(C=C2)C(C)(C)C(O)=O)CC1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Bilastine used for?

DrugCentral lists the following indications for Bilastine: Allergic rhinitis and Urticaria.

How does Bilastine work?

Its molecular targets in DrugCentral include HRH1 (antagonist).

What is the chemical formula of Bilastine?

Bilastine has the molecular formula C28H37N3O3 and a molecular weight of 463.62 g/mol.

Sources

• DrugCentral drug card 4353 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1742423 — compound record and bioactivity
• PubChem CID 185460 — chemical identifiers
• DrugBank DB11591 — drug record
• FDA UNII PA1123N395 — substance identity
• UniProt P35367 (HRH1) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.