Corticorelin

VARIOUS

Key facts

Corticorelin is a drug catalogued in DrugCentral. DrugCentral lists 4 molecular targets, including CRHR1, Crhr2 and Crhr2. Recorded indications include Diagnosis of Hypercortisolism.

• Molecular targets: CRHR1, Crhr2, Crhr2 and CRHR2 (4 listed in DrugCentral).
• Indications: Diagnosis of Hypercortisolism.
• ATC code: V04CD04 (Tests for pituitary function).
• Molecular formula: C208H344N60O63S2; molecular weight 4757.52 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Diagnosis of Hypercortisolism

Mechanism & targets

Molecular targets (4)

Target	Gene	Action	Activity
Corticotropin-releasing factor receptor 1	CRHR1	agonist	Kd 8.48
Corticotropin-releasing factor receptor 2	Crhr2	agonist	Kd 7.90
Corticotropin-releasing factor receptor 2	Crhr2	agonist	Ki 7.80
Corticotropin-releasing factor receptor 2	CRHR2	agonist	Kd 7.40

ATC classification

ATC code	Therapeutic hierarchy
V04CD04	VARIOUS › DIAGNOSTIC AGENTS › OTHER DIAGNOSTIC AGENTS › Tests for pituitary function

Chemical structure

• Molecular formula: C₂₀₈H₃₄₄N₆₀O₆₃S₂
• Molecular weight: 4757.52 g/mol
• CAS number: 86784-80-7
• InChIKey: GBONBLHJMVUBSJ-FAUHKOHMSA-N
• PubChem CID: 16186200

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Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Corticorelin used for?

DrugCentral lists the following indications for Corticorelin: Diagnosis of Hypercortisolism.

How does Corticorelin work?

Its molecular targets in DrugCentral include CRHR1 (agonist), Crhr2 (agonist), Crhr2 (agonist) and CRHR2 (agonist).

What is the chemical formula of Corticorelin?

Corticorelin has the molecular formula C208H344N60O63S2 and a molecular weight of 4757.52 g/mol.

Sources

• DrugCentral drug card 4858 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2107324 — compound record and bioactivity
• PubChem CID 16186200 — chemical identifiers
• DrugBank DB05394 — drug record
• FDA UNII 305OE8862Y — substance identity
• UniProt P34998 (CRHR1) — target protein
• UniProt Q13324 (CRHR2) — target protein

How this page is built: methodology · editorial policy & corrections.