Dexetimide
NERVOUS SYSTEM
Also known as: dexbenzetimide
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Dexetimide is a drug catalogued in DrugCentral. DrugCentral lists 3 molecular targets, including CHRM2, Chrm2 and Chrm1|Chrm4|Chrm5|Chrm3|Chrm2. Recorded indications include Neuroleptic-induced Parkinsonism.
- Molecular targets: CHRM2, Chrm2 and Chrm1|Chrm4|Chrm5|Chrm3|Chrm2 (3 listed in DrugCentral).
- Indications: Neuroleptic-induced Parkinsonism.
- ATC code: N04AA08 (Tertiary amines).
- Molecular formula: C23H26N2O2; molecular weight 362.47 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Neuroleptic-induced Parkinsonism
Mechanism & targets
Molecular targets (3)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | CHRM2 | antagonist | Ki 8.90 |
| Muscarinic acetylcholine receptor M2 | Chrm2 | antagonist | Ki 8.80 |
| Muscarinic acetylcholine receptor | Chrm1|Chrm4|Chrm5|Chrm3|Chrm2 | unknown | IC50 8.48 |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
N04AA08 | NERVOUS SYSTEM › ANTI-PARKINSON DRUGS › ANTICHOLINERGIC AGENTS › Tertiary amines |
Chemical structure
| Molecular formula | C23H26N2O2 |
|---|---|
| Molecular weight | 362.47 g/mol |
| CAS number | 21888-98-2 |
| InChIKey | LQQIVYSCPWCSSD-HSZRJFAPSA-N |
| PubChem CID | 30843 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Dexetimide used for?
DrugCentral lists the following indications for Dexetimide: Neuroleptic-induced Parkinsonism.
How does Dexetimide work?
Its molecular targets in DrugCentral include CHRM2 (antagonist), Chrm2 (antagonist) and Chrm1|Chrm4|Chrm5|Chrm3|Chrm2.
What is the chemical formula of Dexetimide?
Dexetimide has the molecular formula C23H26N2O2 and a molecular weight of 362.47 g/mol.
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Sources
- DrugCentral drug card 831 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL1908364 — compound record and bioactivity
- PubChem CID 30843 — chemical identifiers
- DrugBank DB08997 — drug record
- FDA UNII 43477QYX3D — substance identity
- UniProt P08172 (CHRM2) — target protein
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