Metixene
NERVOUS SYSTEM
Also known as: methixene, methixene HCl, methixene hydrochloride, methixene hydrochloride monohydrate, metixen, metixene HCl, metixene hydrochloride, tremaril, tremonil
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Metixene is an ofm drug catalogued in DrugCentral. DrugCentral lists 3 molecular targets, including BCHE, HTR2C and CHRM1. Recorded indications include Parkinsonism.
- Approval status: ofm.
- Molecular targets: BCHE, HTR2C and CHRM1 (3 listed in DrugCentral).
- Indications: Parkinsonism.
- ATC code: N04AA03 (Tertiary amines).
- Molecular formula: C20H23NS; molecular weight 309.47 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Parkinsonism
Mechanism & targets
Molecular targets (3)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Cholinesterase | BCHE | unknown | IC50 5.80 |
| 5-hydroxytryptamine receptor 2C | HTR2C | antagonist | — |
| Muscarinic acetylcholine receptor M1 | CHRM1 | antagonist | — |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| — | FDA | — | NOVARTIS |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
N04AA03 | NERVOUS SYSTEM › ANTI-PARKINSON DRUGS › ANTICHOLINERGIC AGENTS › Tertiary amines |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Metixene is on its molecule page.
| Molecular formula | C20H23NS |
|---|---|
| Molecular weight | 309.47 g/mol |
| CAS number | 4969-02-2 |
| InChIKey | MJFJKKXQDNNUJF-UHFFFAOYSA-N |
| PubChem CID | 4167 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Metixene used for?
DrugCentral lists the following indications for Metixene: Parkinsonism.
How does Metixene work?
Its molecular targets in DrugCentral include BCHE, HTR2C (antagonist) and CHRM1 (antagonist).
What is the chemical formula of Metixene?
Metixene has the molecular formula C20H23NS and a molecular weight of 309.47 g/mol.
Browse: all drugs starting with M · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 1780 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL1200426 — compound record and bioactivity
- PubChem CID 4167 — chemical identifiers
- DrugBank DB00340 — drug record
- FDA UNII 32VY6L26ZW — substance identity
- DailyMed: FDA labels for Metixene — current prescribing information (label search)
- UniProt P28335 (HTR2C) — target protein
- UniProt P11229 (CHRM1) — target protein
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.