Emetine

ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS

Key facts

Emetine is a drug catalogued in DrugCentral. DrugCentral lists 7 molecular targets, including NS5, ADRA2A and ADRA2C.

• Molecular targets: NS5, ADRA2A, ADRA2C and Adra1b (7 listed in DrugCentral).
• ATC code: P01AX02 (Other agents against amoebiasis and other protozoal diseases).
• Molecular formula: C29H40N2O4; molecular weight 480.65 g/mol.

Mechanism & targets

Molecular targets (7)

Target	Gene	Action	Activity
NS5	—	unknown	EC50 8.06
Alpha-2A adrenergic receptor	ADRA2A	unknown	Ki 7.85
Alpha-2C adrenergic receptor	ADRA2C	unknown	Ki 7.58
Alpha-1B adrenergic receptor	Adra1b	unknown	Ki 5.97
Alpha-1D adrenergic receptor	ADRA1D	unknown	Ki 5.58
Alpha-1A adrenergic receptor	Adra1a	unknown	IC50 5.19
Putative hydrolase RBBP9	RBBP9	unknown	IC50 5.11

ATC classification

ATC code	Therapeutic hierarchy
P01AX02	ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS › ANTIPROTOZOALS › AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES › Other agents against amoebiasis and other protozoal diseases
P01AX52	ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS › ANTIPROTOZOALS › AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES › Other agents against amoebiasis and other protozoal diseases

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Emetine is on its molecule page.

• Molecular formula: C₂₉H₄₀N₂O₄
• Molecular weight: 480.65 g/mol
• CAS number: —
• InChIKey: AUVVAXYIELKVAI-CKBKHPSWSA-N
• PubChem CID: 10219

CC[C@H]1CN2CCC3=CC(OC)=C(OC)C=C3[C@@H]2C[C@@H]1C[C@H]1NCCC2=CC(OC)=C(OC)C=C12

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Emetine work?

Its molecular targets in DrugCentral include NS5, ADRA2A, ADRA2C and Adra1b.

What is the chemical formula of Emetine?

Emetine has the molecular formula C29H40N2O4 and a molecular weight of 480.65 g/mol.

Sources

• DrugCentral drug card 1001 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL493439 — compound record and bioactivity
• PubChem CID 10219 — chemical identifiers
• DrugBank DB13393 — drug record
• FDA UNII X8D5EPO80M — substance identity
• UniProt P08913 (ADRA2A) — target protein
• UniProt P18825 (ADRA2C) — target protein
• UniProt P25100 (ADRA1D) — target protein
• UniProt O75884 (RBBP9) — target protein

How this page is built: methodology · editorial policy & corrections.